Results 61 to 70 of about 5,495 (183)

Discovery of a Dual‐Target DNAzyme for Clostridioides difficile and Listeria monocytogenes Diagnostics

ChemistryEurope, Volume 4, Issue 3, March 2026.
A newly discovered fluorogenic DNAzyme, RFD‐CD3, enables rapid and sensitive detection of Clostridioides difficile and—unexpectedly—Listeria monocytogenes, making it the first dual‐responsive DNAzyme for two unrelated bacterial pathogens. Its strong catalytic efficiency, pH‐tolerant activity, and modular trans‐acting design position it as a promising ...
Soyeon Lee, Dingran Chang, Jimmy Gu, Bruno J. Salena, Yingfu Li   +4 more
wiley   +1 more source

Toxic Megacolon – the Complication of an Infection with Clostridium difficile after an Odontogenic Abscess. Case Presentation

Journal of Interdisciplinary Medicine, 2019
Background:Clostridium difficile (CD) is the major cause of nosocomial antibiotic-associated infections, having as main manifestation diarrhea and life-threatening inflammation of the colon.
Suciu Nicolae, Benedek Zalán, Sorlea Sorin, Coroș Marius Florin   +3 more
doaj   +1 more source

Honokiol and Magnolol Exert an Anti‐Inflammatory Effect by Inhibiting JAK2/STAT3/IL17 Signalling in a Rat Model of Ulcerative Colitis: A Combination of Bioinformatics and Experimental Study

Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT Ulcerative colitis (UC) is a chronic, inflammatory bowel disease with limited clinical treatment. Traditional Chinese medicinal ingredients honokiol and magnolol have potential anti‐inflammatory and gastrointestinal protective effects. However, their anti‐inflammatory potential has not been investigated in UC.
Zhaoxu Cai, Shaojun Lu, Jingan Chen, Xiaoshan Yang, Junlin Lu, Changwen Feng   +5 more
wiley   +1 more source

Inflammatory Bowel Diseases: the Surgical Perspective [PDF]

Modern Medicine, 2019
Inflammatory bowel diseases (IBD), namely Crohn’s disease and ulcerative colitis, are relatively rare diseases in our country, known as a low prevalence geographic region.
SOCEA Bogdan, DUMITRESCU Dan, BRATU Ovidiu Gabriel , CARAP Alexandru Constantin, BADIU Dumitru Cristinel, BOLOCAN Alexandra, PADURARU Dan Nicolae, MISCHIANU Dan, CONSTANTIN Vlad Denis   +8 more
doaj   +1 more source

Exploratory Clinical Study to Evaluate the Efficacy and Safety of Sulfasalazine for Immune Checkpoint Inhibitor (ICI)‐Induced Colitis

JGH Open, Volume 10, Issue 2, February 2026.
ABSTRACT Background The first‐choice treatment for immune checkpoint inhibitor (ICI)‐induced colitis is steroids; however, side effects may occur and survival may be reduced. Sulfasalazine (SSZ) is primarily used for inflammatory bowel disease but studies on ICI‐induced colitis are scarce.
Mariko Kobayashi, Takeshi Yamada, Shunsuke Ueyama, Yoshiyuki Yamamoto, Akinori Sugaya, Yoshinori Hiroshima, Takashi Mamiya, Junji Hattori, Shintaro Akiyama, Bryan J. Mathis, Kiichiro Tsuchiya   +10 more
wiley   +1 more source

A young leukemic patient with unusual catastrophic intestinal complication

Indian Journal of Pathology and Microbiology, 2015
A 14-year-old child with acute lymphoblastic leukemia who had completed induction chemotherapy presented with fever and diffuse musculoskeletal pains which was thought to be a constellation of myositis, arthralgias and arthritis.
Kim Vaiphei, Amita Trehan, Man Updesh Singh Sachdeva, Pankaj Malhotra   +3 more
doaj   +1 more source

Preliminary non‐comparative evaluation of an adapted colonoscopy preparation protocol for dogs using sodium picosulphate and magnesium citrate

Veterinary Record, Volume 198, Issue 3, Page e101-e107, 31 January/7 February 2026.
Abstract Background Challenges associated with bowel cleansing protocols for canine colonoscopy include practical applicability and inadequate preparations. This study aimed to describe and evaluate an adapted protocol to simplify colonoscopy preparation in dogs.
Julia Elia da Silva Paranhos, Melissa Guillen Gonçalves de Souza, Daniela Araujo de Sousa, Debora Costabile Soibelman, Sabrina Martins da Costa Ferreira, Juliana da Silva Leite, Bruno Penna, Ana Maria Reis Ferreira   +7 more
wiley   +1 more source

Pseudomembranous colitis and toxic megacolon due to C. difficile in an inpatient hospitalized for home accident

Clinical Management Issues, 2015
Clostridium difficile infection (CDI) is the main cause of hospital-acquired diarrhea. It can result in symptoms ranging from moderate diarrhea to pseudomembranous colitis.
Piergiorgio Chiriacò
doaj   +1 more source

Inflammatory bowel disease and metabolic reprogramming: From pathological mechanisms to targeted interventions

Interdisciplinary Medicine, Volume 4, Issue 1, January 2026.
This review explores the role of metabolic reprogramming in inflammatory bowel disease (IBD) by focusing on immune and epithelial cell metabolism, microbial metabolites, and their impact on inflammation. It discusses emerging metabolic therapies and emphasizes the importance of personalized microbiota‐targeted approaches to improve clinical outcomes in
Zemin Tian, Yinde Huang, Ying Wang, Chenyu Zhao, Zhaokai Zhou, Hua Yang, Yuan Qiu   +6 more
wiley   +1 more source

Clostridioides difficile infection leading to fulminant colitis with toxic megacolon

Autopsy and Case Reports, 2023
Clostridioides difficile infection (CDI) is the culprit of millions of nosocomial infections in the United States. Programs that successfully decrease its incidence, therefore, render cost savings for the healthcare system.
Fareed Rajack, Shawn Medford, Tammey Naab   +2 more
doaj