Results 111 to 120 of about 230,179 (340)

Screening and application of aptamers to Staphylococcus aureus Toxic Shock Syndrome Toxin-1 [PDF]

open access: yes, 2016
摘要 目的:金黄色葡萄球菌(Staphylococcusaureus)分泌的毒性休克综合征毒素-1(ToxicShockSyndromeToxin-1,TSST-1)引发中毒性休克综合征(ToxicShockSyndrome,TSS),通过激活T淋巴细胞使其活化、增殖,引起强烈的免疫应答。目前针对TSST-1本身的治疗手段不多,合成寡核苷酸文库和亲和力筛选作为获得高亲和力、高特异性适配体(Aptamer)的一种方便、快捷、有效的方法。本研究利用指数富集的配体系统进化技术 ...
陈弘炜
core  

Possible Skull Base Erosion After Prolonged Frontal Sinus Stenting [PDF]

open access: yes, 2019
Frontal sinus stenting is widely used with the goal of maintaining nasofrontal duct patency after sinus surgery. The general recommendation is to leave stents in place for 6 months; however, prolonged stenting up to 6 years has been reported with no ...
Ching, Harry H., MD   +3 more
core   +2 more sources

Fulminant Streptococcal Toxic Shock Syndrome

open access: yesJournal of the Royal College of Physicians of Edinburgh, 2018
We present a case of a previously healthy 37-year-old male who developed fever, nausea, vomiting, diarrhoea, and hypovolaemia. Within 5.5 h he presented with tachycardia, tachypnoea, became hypotensive and displayed a diffuse erythematous rash. In the following hours he developed persistent hypotension, acute respiratory distress syndrome, liver ...
Zavala, S., Arias, M., Legua, P.
openaire   +2 more sources

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska   +4 more
wiley   +1 more source

Invasive streptococcal group A infection in children: а review of the literature and a clinical case of the toxic shock syndrome and complicated community-acquired pneumonia in a child with lung malformation

open access: yesAlʹmanah Kliničeskoj Mediciny, 2018
Streptococcal group A  infection (SGAI) remains an important cause of morbidity and mortality in children. In the recent years, the spread of new highly virulent strains of Streptococcus pyogenes, capable of producing cytolysins and pyrogenic exotoxins ...
E. R. Meskina, M. K. Khadisova
doaj   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

open access: yesFood Bioengineering, EarlyView.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi   +4 more
wiley   +1 more source

The problem of proliferation methicillin-resistant S. aureus [PDF]

open access: yes, 2017
Staphylococci are natural inhabitant of human and animal skin but sometimes they can cause infections affecting many organs (endocarditis, toxic shock syndrome, sepsis, pneumonia and arthritis). Most staphylococci are responsible for skin infections such
Nazbar, E., Shubin, P.
core  

Rethinking the role of alpha toxin in Clostridium perfringens-associated enteric diseases : a review on bovine necro-haemorrhagic enteritis [PDF]

open access: yes, 2017
Bovine necro-haemorrhagic enteritis is an economically important disease caused by Clostridium perfringens type A strains. The disease mainly affects calves under intensive rearing conditions and is characterized by sudden death associated with small ...
Deprez, Piet   +6 more
core   +3 more sources

Advanced extracellular vesicle immunotherapy

open access: yesFlexMat, EarlyView.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang   +6 more
wiley   +1 more source

Infectious Shock and Toxic Shock Syndrome Diagnoses in Hospitals, Colorado, USA

open access: yesEmerging Infectious Diseases, 2013
In Colorado, USA, diagnoses coded as toxic shock syndrome (TSS) constituted 27.3% of infectious shock cases during 1993–2006. The incidence of staphylococcal TSS did not change significantly overall or in female patients 10–49 years of age but increased ...
Michael A. Smit   +2 more
doaj   +1 more source

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