MedComm, Volume 7, Issue 7, July 2026.Proposed mechanism of middle‐dose sorafenib modulates redox homeostasis via c‐Raf/HSP90/G6PD axis to attenuate hepatic IRI. This study demonstrates that middle‐dose sorafenib mitigates hepatic IRI through the c‐Raf/HSP90/G6PD axis to enhance pentose phosphate pathway‐mediated antioxidant defense and redox homeostasis, thereby alleviating inflammatory ...
Fengqiang Gao +13 more
wiley +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
MedComm, Volume 7, Issue 7, July 2026.Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Genetic Characterization of <i>Staphylococcus aureus</i> Isolates Associated with Toxic Shock Syndrome Toxin Production: An Epidemiological and Bioinformatics Approach. [PDF]
Toxins (Basel)Aguirre-Sánchez JR +3 more
europepmc +1 more source
The pivotal role of β‐lactone stereochemistry in the development of SARS‐CoV‐2 Mpro inhibitors
Protein Science, Volume 35, Issue 7, July 2026.Abstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Katarzyna Świderek, Vicent Moliner
wiley +1 more source
Managing toxic shock syndrome in immunosuppressed patient after liver transplantation from trauma to triumph: A case report. [PDF]
World J Clin CasesDomislović V +7 more
europepmc +1 more source
Epigenetic Regulation of Immune Dysfunction in Chronic Prostatitis/Chronic Pelvic Pain Syndrome
The Prostate, Volume 86, Issue 10, Page 1124-1133, July 2026.ABSTRACT Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent and debilitating condition with unclear etiology. Increasing evidence implicates immune dysregulation, yet the molecular mechanisms underlying impaired immune regulation remain poorly defined. This study investigated the role of altered immune responses within
Praveen Thumbikat +8 more
wiley +1 more source
Dry Cleaning and Post‐Cleaning Strategies in Food Processing Facilities: A Scoping Review
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.ABSTRACT Effective dry cleaning and post‐cleaning treatments are essential for maintaining food safety in dry‐food processing environments where water use must be minimized. This scoping review mapped and synthesized empirical research on minimal‐water cleaning methods applied to industrial surfaces, focusing on their efficacy against microbial and ...
Zahra Shahbazi +3 more
wiley +1 more source
Toxic Shock Syndrome in a 45-Year-Old Woman Possibly Associated with Tampon Use: A Case Report of Multiorgan Failure Due to <i>Streptococcus agalactiae</i>. [PDF]
DiseasesZavidić T, Dejhalla E, Zahirović D.
europepmc +1 more source
Contrast‐enhanced CT—Nephrotoxic or not? A critical review of propensity‐score‐adjusted studies
Journal of Internal Medicine, Volume 300, Issue 1, Page 5-25, July 2026.Abstract Retrospective, propensity‐score‐adjusted (PSA) studies have indicated to practitioners in the field that contrast‐induced acute kidney injury (AKI) after contrast‐enhanced CT (CECT) is of minor importance or even non‐existent. This has led to controversies between clinicians demanding CECT not to miss any diagnoses and radiologists reluctant ...
Ulf Nyman +6 more
wiley +1 more source