Results 71 to 80 of about 230,179 (340)

Persistence survey of Toxic Shock Syndrome toxin-1 producing Staphylococcus aureusand serum antibodies to this superantigen in five groups of menstruating women [PDF]

, 2010
Background: Menstrual Toxic Shock Syndrome (mTSS) is thought to be associated with the vaginal colonization with specific strains of Staphylococcus aureus TSST-1 in women who lack sufficient antibody titers to this toxin.
Andrea M DuBois, Andrew B Onderdonk, Jeffrey Parsonnet, John E Wild, Jon L Seymour, Mary L Delaney, Melanie A Hansmann, Michaelle B Jones, Paul A Modern   +8 more
core   +3 more sources

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Periocular Necrotizing Fasciitis with Toxic Shock Syndrome

Case Reports in Ophthalmology, 2018
Purpose: To report a case of periocular necrotizing fasciitis with toxic shock syndrome. Methods: This is a case report of a previously healthy 69-year-old woman with left preseptal eyelid infection that spread rapidly and deteriorated into necrosis of ...
Tri Rejeki Herdiana, Yasuhiro Takahashi, Ma. Regina Paula Valencia, Marian Grace Ana-Magadia, Hirohiko Kakizaki   +4 more
doaj   +1 more source

Etiological Profile and Treatment Outcome of Epistaxis at a Tertiary Care Hospital in Northwestern Tanzania: A Prospective Review of 104 Cases. [PDF]

, 2011
Epistaxis is the commonest otolaryngological emergency affecting up to 60% of the population in their lifetime, with 6% requiring medical attention. There is paucity of published data regarding the management of epistaxis in Tanzania, especially the ...
A Daudia, Abhay-Gupta, AK Nemer, B Feusi, C Huang, C Yueng-Hsiang, CM Nash, D Biswas, DJ Pallin, F Pond, GTA Ijaduola, I Kaygusuz, JAE Eziyi, Japhet M Gilyoma, JS Rodney, KR Iseh, LER Pope, LH Wurman, M Bernius, MS Awan, N Umapathy, NC Mgbor, OV Akinpelu, Phillipo L Chalya, PJ Andersen, R Urvashi, S Chaiyasate, S Varshney, SH Ciaran, TWM Walker   +29 more
core   +2 more sources

Clinical and Molecular Epidemiology of Staphylococcal Toxic Shock Syndrome in the United Kingdom

Emerging Infectious Diseases, 2018
Nonmenstrual TSS is now more common, and better understanding will improve prevention interventions.
Hema Sharma, Debra Smith, C. Turner, L. Game, B. Pichon, R. Hope, R. Hill, A. Kearns, S. Sriskandan   +8 more
semanticscholar   +1 more source

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

Advanced Science, EarlyView.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang, Maodong Leng, Chenchen Sun, Jingyu Cao, Linfei Li, Yangyang Jia, Yongshuai Han, Yuchun Liu, Yaodong Zhang, Chenglong Zhang, Yingli Men, Ningyuan Liu, Yibing Cheng, Yixia Zhang, Ya Li, Zhenlong Li, Lidan Cui, Xiangzhan Zhu   +17 more
wiley   +1 more source

Accessory gene regulator types of Staphylococcus aureus isolated in Gorgan, North of Iran [PDF]

, 2014
Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans.
Bibalan, M.H., Ghaemi, A., Ghaemi, E.A., Javid, N., Shakeri, F.   +4 more
core   +1 more source

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, EarlyView.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Spontaneous perforation of the cystic duct in streptococcal toxic shock syndrome: a case report

Journal of Medical Case Reports, 2008
Introduction Streptococcal toxic shock syndrome is a complication of group A streptococcal infection, most often originating from the skin. The syndrome is characterized by fever, hypotension and multiple organ failure.
Endeman Henrik, Ligtenstein David A, Oudemans-van Straaten Heleen M   +2 more
doaj   +1 more source