Results 81 to 90 of about 230,179 (340)

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, EarlyView.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source

Clinical aspects for differential diagnosis of Kawasaki disease shock syndrome: a case control study

BMC Pediatrics, 2021
Background Because of the absence of a specific diagnostic test and pathognomonic clinical features, physicians must rely on the presence of specific clinical criteria and laboratory data that support the diagnosis of KD.
Woo Young Park, Sang Yun Lee, Gi Beom Kim, Mi Kyoung Song, Hye Won Kwon, Eun Jung Bae, Eun hwa Choi, June Dong Park   +7 more
doaj   +1 more source

Prospective surveillance of invasive group a streptococcal disease, Fiji, 2005-2007. [PDF]

, 2001
We undertook a prospective active surveillance study of invasive group A streptococcal (GAS) disease in Fiji over a 23-month period, 2005-2007. We identified 64 cases of invasive GAS disease, which represents an average annualized all-ages incidence of 9.
Andrew C. Steer, Adam Jenney, Joseph Kado, Michael F. Good, Michael Batzloff, Lepani Waqatakirewa, E. Kim Mullholland, Jonathan R. Carapetis, Steer, Hoge, Carapetis, Lamagni, O'Brien, Li, O’Loughlin, Steer, Beall, Berkley, Norton, Carapetis, Zimmet, Collins, Finger, Tiu, O'Grady, Zurawski, Tyrrell, Eriksson, Bessen, Wagner, Sharma, Bisno, Kotloff, McNeil   +33 more
core   +5 more sources

A confirmed case of toxic shock syndrome associated with the use of a menstrual cup

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2015
Toxic shock syndrome (TSS) is caused by toxic bacteria and has been associated with prolonged, continual use of high-absorbency tampons. This article documents the first case of TSS associated with the use of a menstrual cup in a 37-year-old woman.
Michael A. Mitchell, Steve Bisch, Shannon Arntfield, Seyed M. Hosseini-Moghaddam   +3 more
semanticscholar   +1 more source

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

Advanced Science, EarlyView.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi, Di Tang, Johan Malmström, Yasaman Karami, Hamed Khakzad   +4 more
wiley   +1 more source

Staphylococcal toxic shock syndrome associated with disseminated intravascular coagulopathy leading to compartment syndrome of the lower extremity

Burns Open, 2017
We report a case of a 56-year old multimorbid male patient who was transferred to our specialized burn center with a combination of extensive blistering with underlying deep tissue necrosis, disseminated intravascular coagulation and compartment syndrome
Martin F. Vierhapper, Denise Traxler, Christine Radtke   +2 more
doaj   +1 more source

Staphylococcus aureus Infections in the Paediatric Intensive Care Unit: Illustrated Cases

Case Reports in Pediatrics, 2021
Staphylococcus aureus is known to be one of the most common gram-positive microorganisms and an important pathogen associated with sepsis and toxic shock.
Kam Lun Hon, Ronald C. M. Fung, Karen K. Y. Leung, Alexander K.C. Leung, Wun Fung Hui, Wing Lum Cheung   +5 more
doaj   +1 more source

Tissue eosinophilia and eosinophil degranulation in Riedel's invasive fibrous thyroiditis. [PDF]

, 1996
The etiology of Riedel's invasive fibrous thyroiditis (IFT) has remained obscure. This rare disorder has been confused in the past with the more common fibrous variant of Hashimoto's disease.
Bahn, R. S., Gleich, G. J., Goellner, J. R., Hay, I. D., Heufelder, Armin E.   +4 more
core   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Necrotizing Fasciitis and Toxic Shock Syndrome from Clostridium septicum following a Term Cesarean Delivery

Case Reports in Obstetrics and Gynecology, 2014
Necrotizing fasciitis and toxic shock syndrome are life-threatening conditions that can be seen after any surgical procedure. With only 4 previous published case reports in the obstetrics and gynecology literature of these two conditions occurring ...
B. H. Rimawi, W. Graybill, J. Y. Pierce, M. Kohler, E. A. Eriksson, M. T. Shary, B. Crookes, D. E. Soper   +7 more
doaj   +1 more source