Results 261 to 270 of about 4,117,947 (390)

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Author Correction: Humidifier disinfectant, sodium dichloroisocyanurate (NaDCC): assessment of respiratory effects to protect workers’ health

Scientific Reports
DongSeok Seo, Yong-Hoon Lee, JiMin Jo
doaj   +1 more source

ToxACoL: an endpoint-aware and task-focused compound representation learning paradigm for acute toxicity assessment. [PDF]

Nat Commun
Lu J, Wu L, Li R, Wan M, Yang J, Zan P, Bai H, He S, Bo X.   +8 more
europepmc   +1 more source

The toxic action of expired air [PDF]

, 1893
John Haldane, John L. Smith
openalex   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Phenytoin-induced Ogilvie syndrome: A rare case report. [PDF]

SAGE Open Med Case Rep
Sabu J, Madapat KJ, Baby NK.
europepmc   +1 more source

Special Discussion On The Origin, Symptoms, Pathology, Treatment, And Prophylaxis Of Toxic Jaundice Observed In Munition Workers.

, 1917
T. M. Legge
openalex   +1 more source

Non-toxicity to animals of ryegrass endophyte and other endophytic fungi of New Zealand grasses [PDF]

, 1958
I. J. Cunningham
openalex   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Digoxin toxicity with therapeutic serum digoxin concentrations. [PDF]

Toxicol Rep
Graafsma J, Cimic N, Dijkman M, Gresnigt FMJ, Mitrovic D, Smit C.   +5 more
europepmc   +1 more source