Results 271 to 280 of about 4,117,947 (390)
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Exposure to perfluorooctane sulfonate (PFOS) has been associated with lower bone density and the occurrence of osteoporosis in human studies, but the effects and mechanisms of PFOS induces bone loss is not well understood.
Liming Xue+9 more
doaj
Impact of halogenation on scaffold toxicity assessed using HD-GEM machine learning model. [PDF]
Boya BR, Lee JH, Choi JM, Lee J.
europepmc +1 more source
Antimicrobial Titanium–Copper Alloys: The Role of Microstructure in Arc‐Melted Compositions
Copper‐containing titanium alloys show promise in combating orthopedic implant infections. This study explores the influence of heat treatment on Ti‐11.5Cu and Ti‐33Cu alloys, revealing that larger Ti2Cu precipitates (≈5 μm) enhance antimicrobial efficacy through increased surface contact. Results suggest contact sterilization is the primary mechanism,
Daisy Rabbitt+5 more
wiley +1 more source
Influence of Genetic Variation of GST, CYP, and ABC on the Safety and Efficacy of Cyclophosphamide-Based Therapy. [PDF]
Yao ZW+9 more
europepmc +1 more source
CHRONIC TOXICITY OF DEXTRAN SULPHATE IN RABBITS [PDF]
H Hint, Ary Wolfgang Richter
openalex +1 more source
Highly textured CeO2 nanowires and nanoporous thin films are successfully synthesized by water dissolution of Sr3Al2O6 (SAO) from the SAO:CeO2 vertically aligned nanocomposites (VANs). The morphology of CeO2 can be varied by VAN composition. It demonstrates a new method for synthesizing nanostructured CeO2 without chemical etching or complex micro ...
Benson Kunhung Tsai+8 more
wiley +1 more source