Results 21 to 30 of about 780,751 (311)

Review of the methods to determine the hazard and toxicity of pesticides to bumblebees

, 2001
Methods to determine the impact of pesticides on bumblebees are described. They are classified into laboratory tests to determine the acute toxicity and the hazard to bumblebees, (semi) field tests, and brood tests.
Steen, J.J.M., van der, van der Steen, J.J.M., Jozef J.M. van der Steen, van Der Steen, Jozef   +3 more
core   +1 more source

A Pilot Study on Single-dose Toxicity Testing of Hominis placenta Pharmacopuncture in Sprague-Dawley Rats

Journal of Pharmacopuncture, 2015
Objectives: This study was performed to analyze the toxicity and to find the lethal dose of the test substance Hominis placenta pharmacopuncture when used as a single-dose in 6 week old, male and female Sprague-Dawley (SD) rats.
Yoo-Hwan Lee, Hyun-Min Yoon, Kyung-Jeon Jang, Cheol-Hong Kim   +3 more
doaj   +1 more source

Electrochemical peroxidation of contaminated water and assessment of the toxicity using existing and novel bioassays [PDF]

, 2011
The treatment of wastewater and monitoring of its toxicity is essential before discharging it to the environment. This study focuses on assessing the toxicity of wastewater following treatment using the electrochemical peroxidation process (ECP). Three
Kokkali, Varvara
core  

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Safety testing of acellular pertussis vaccines: Use of animals and 3Rs alternatives

Human Vaccines & Immunotherapeutics, 2017
The current test of acellular Bordetella pertussis (aP) vaccines for residual pertussis toxin (PTx) is the Histamine Sensitization test (HIST), based on the empirical finding that PTx sensitizes mice to histamine.
Marieke Hoonakker, Juan Arciniega, Coenraad Hendriksen   +2 more
doaj   +1 more source

Green synthesis of SeNPs using Sonchus maritimus based nanosized metal oxides for in vitro biological applications and in vivo acute toxicity evaluation [PDF]

Kragujevac Journal of Science, 2023
This investigation aimed to characterize the green synthesized selenium nanoparticles using Sonchus maritimus L. extract and evaluate their antioxidant and antibacterial properties.
Chetehouna Sara, Derouiche Samir, Réggami Yassine   +2 more
doaj  

Comparative toxicity assessment of nanosilver on three Daphnia species in acute, chronic and multi-generation experiments

, 2013
The antibacterial properties of nanosilver have led to a versatile application spectrum including medical purposes and personal care products. However, the increasing use of nanosilver has raised concerns about its environmental impacts.
Völker, Carolin, Cathinka Boedicker, Matthias Oetken (74114), Boedicker, Cathinka, Oehlmann, Jörg, Oetken, Matthias, Matthias Oetken, Cathinka Boedicker (467537), Daubenthaler, Jan, Jan Daubenthaler (467538), Jörg Oehlmann, Carolin Völker (467536), Jan Daubenthaler, Jörg Oehlmann (74061), Carolin Völker   +14 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source