Results 171 to 180 of about 435,111 (310)

Heavy metal pollution and risk assessment by the battery of toxicity tests. [PDF]

Sci Rep, 2020
Khan MS, Javed M, Rehman MT, Urooj M, Ahmad MI.   +4 more
europepmc   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Microbiological toxicity tests using standardized ISO/OECD methods-current state and outlook. [PDF]

Appl Microbiol Biotechnol
Strotmann U, Durand MJ, Thouand G, Eberlein C, Heipieper HJ, Gartiser S, Pagga U.   +6 more
europepmc   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Adverse effects in traditional and alternative toxicity tests. [PDF]

Regul Toxicol Pharmacol
Browne P, Paul Friedman K, Boekelheide K, Thomas RS.   +3 more
europepmc   +1 more source

Toxicity of Nanoparticulate Nickel to Aquatic Organisms: Review and Recommendations for Improvement of Toxicity Tests. [PDF]

Environ Toxicol Chem, 2020
Meyer JS, Lyons-Darden T, Garman ER, Middleton ET, Schlekat CE.   +4 more
europepmc   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Sediment Toxicity Tests: A Critical Review of Their use in Environmental Regulations. [PDF]

Environ Toxicol Chem
Leppanen MT, Sourisseau S, Burgess RM, Simpson SL, Sibley P, Jonker MTO.   +5 more
europepmc   +1 more source

Key Opportunities to Replace, Reduce, and Refine Regulatory Fish Acute Toxicity Tests. [PDF]

Environ Toxicol Chem, 2020
Burden N, Benstead R, Benyon K, Clook M, Green C, Handley J, Harper N, Maynard SK, Mead C, Pearson A, Ryder K, Sheahan D, van Egmond R, Wheeler JR, Hutchinson TH.   +14 more
europepmc   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source