Results 101 to 110 of about 346,022 (311)
Long‐Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins
Advanced Science, EarlyView.Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.Jianhui Guo, Xia Zhong, Petros Koutrakis, Carolina L. Zilli Vieira, Feifei Si, Yaqi Wang, Xinyao Lian, Yi Fan, Zhaokun Wang, Shaodan Huang, Jing Li +10 morewiley +1 more sourceMachine Learning‐Driven Prediction of Microplastic Aging Processes and Environmental Risk Assessment Across Multi‐Media Systems
Advanced Science, EarlyView.This perspective proposes a cohesive machine learning strategy to decode microplastic aging. It advocates for Federated Learning to dismantle global data silos and introduces the TRACE framework (TRansport, Aging, Corona, Ecotoxicity). By integrating physics‐informed modeling with causal discovery, this approach bridges the laboratory‐field gap to ...Yaping Lyu, Xinran Qiu, Xing Li, Tianhuan Yang, Xuetao Guo, Hao Qiu, Peng Zhang +6 morewiley +1 more sourcetoxicology (5)
Toxicology Presentation slides: signs and symptoms at various concentrations of ...core Collaborative development of predictive toxicology applications
, 2010 OpenTox provides an interoperable, standards-based Framework for the support of predictive toxicology data management, algorithms, modelling, validation and reporting.Melagraki, G, Ghosh, I., Tcheremenskaia, O., Alexey Zakharov, Gütlein, M., Afantitis, A, Karwath, A., Helma, C, Wicker Joerg, Lagunin Alexey, Ivelina Nikolova, Poroikov, V., Hardy, B, Douglas, N., Patel, Hitesh, Buchwald, Fabian, Wicker, J., Escher, Sylvia, Hardy, B., Lagunin, A., Helma Christoph, Buchwald, F, Maunz, Andreas, Poroikov Vladimir, Martin Gutlein, Gutlein, Martin, Jeliazkov Vedrin, Girschick, T., Douglas, N, Georgia Melagraki, Jeliazkov, V., Druzhilovsky, Dmitry, Sylvia Escher, Kramer, S, Tcheremenskaia Olga, Melagraki, G., Poroikov, Vladimir, Romualdo Benigni, Benigni, R., Fabian Buchwald, Gallagher, D., Nikolova Ivelina, Filimonov, D, Karwath Andreas, Rautenberg, M., Dmitry Filimonov, Natalia Skvortsova, Tobias Girschick, Jeliazkova, N., Gütlein Martin, Ghosh Indira, Karwath, A, Micha Rautenberg, Nikolova, Ivelina, Filimonov, D., Chawla, Sunil, Filimonov Dmitry, Gallagher, D, Zakharov, A., Rautenberg, Micha, Gloriozova Tatyana, Alexey Lagunin, Indira Ghosh, Surajit Ray, Filimonov, Dmitry, Hardy, Barry J., Girschick Tobias, Lagunin, A, Skvortsova, N, Gloriozova, T., Escher, S, Kramer Stefan, Jeliazkova, N, Girschick, T, Tcheremenskaia, Olga, Vladimir Poroikov, Ray, Surajit, Buchwald Fabian, Sopasakis, P, Antreas Afantitis, Melagraki Georgia, Ray, S, Nina Jeliazkova, Novikov, Sergey, Maunz, A., Joerg Wicker, Skvortsova Natalia, Nicki Douglas, Helma, Christoph, Gutlein, M, Zakharov, A, Girschick, Tobias, Hardy Barry, Karwath, Andreas; id_orcid, Ray Surajit, Andreas Karwath, Hardy, Barry, Druzhilovsky Dmitry, Nikolova, I., Maunz, A, Kramer, S., Tcheremenskaia, O, Sopasakis, P., Nikolova, I, Sopasakis, Pantelis, Jeliazkova Nina, Rautenberg Micha, Patel Hitesh, Druzhilovsky, D., Afantitis, A., Zakharov, Alexey V., Zakharov Alexey, Escher, S., Druzhilovsky, D, Melagraki, Georgia, Douglas, Nicki, Sopasakis, Pantelis; id_orcid, Gloriozova, T, Jeliazkova, Nina, Haralambos Sarimveis, Helma, C., Tatyana Gloriozova, Benigni Romualdo, Patel, H., Sopasakis Pantelis, Skvortsova, Natalia, Rautenberg, M, Afantitis Antreas, Barry Hardy, Pantelis Sopasakis, Gallagher, David, Sarimveis, Haralambos, Karwath, Andreas, Jeliazkov, V, Afantitis, Antreas, Buchwald, F., Benigni, R, Wicker, Joerg, Ray, S., Lagunin, Alexey, Sarimveis, H., Benigni, Romualdo, Kramer, Stefan, Sergey Novikov, Novikov, S., Zakharov, Alexey, Chawla, S., Sarimveis Haralambos, Novikov, S, Stefan Kramer, Ghosh, Indira, Olga Tcheremenskaia, Wicker, Jörg, Novikov Sergey, Escher Sylvia, Vedrin Jeliazkov, Hitesh Patel, Poroikov, V, Chawla, S, Andreas Maunz, Sunil Chawla, Jeliazkov, Vedrin, Patel, H, Gallagher David, Sarimveis, H, Dmitry Druzhilovsky, Wicker, J, Christoph Helma, Chawla Sunil, Maunz Andreas, Ghosh, I, Gloriozova, Tatyana, Douglas Nicki, David Gallagher, Skvortsova, N. +174 morecore +1 more sourceLessons From Drug Discovery for Cryoprotective Agent Design: An AI‐Oriented Perspective
Advanced Science, EarlyView.Cryoprotectant design is reframed through the lens of drug discovery as a multiparameter optimization problem. This perspective highlights how AI and systematic design strategies could enable safer, more effective cryoprotectants, while identifying key limitations that currently constrain predictive progress in cryobiology. ABSTRACT
Cryopreservation is Dominika Wilczok, Jesús Valdés‐Hernández, Varinia Bernales, Alán Aspuru‐Guzik, Alex Zhavoronkov +4 morewiley +1 more sourceA Wireless 3D Magneto‐Mechanical Stimulation Platform Drives In Situ Chondrogenic Commitment of Endogenous MSCs
Advanced Science, EarlyView.An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.Zhenguang Li, Li Peng, Laiya Lu, Yingying Wang, Xiaolei Chen, Feng Yin, Cuijun Deng, Yu Cheng +7 morewiley +1 more source
