Results 71 to 80 of about 706,933 (359)
Advanced Functional Materials, EarlyView.This study develops a novel atomic engineering strategy to fine‐tune the spin state of α‐Fe2O3 catalysts toward a medium‐spin state, thereby modulating peroxymonosulfate activation and selectively yielding surface‐bound radicals. Compared with free radicals, surface‐bound radicals exhibit moderated oxidation potential, extended lifespan, surface ...
Shuyu Wang +7 more
wiley +1 more source
Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells [PDF]
, 2010 Background - Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
Alink, G.M. +7 more
core +2 more sources
Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
Advanced Healthcare Materials, EarlyView.We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
In vitro 3D skin culture and its sustainability in toxicology: a narrative review
Artificial Cells, Nanomedicine, and BiotechnologyIn current toxicological research, 2D cell cultures and animal models are well- accepted and commonly employed methods. However, these approaches have many drawbacks and are distant from the actual environment in human.
Syafira Masri +5 more
doaj +1 more source
Multi-Behavioral Endpoint Testing Of An 87-Chemical Compound Library In Freshwater Planarians [PDF]
, 2018 There is an increased recognition in the field of toxicology of the value of medium-to-high-throughput screening methods using in vitro and alternative animal models.
Collins, Eva-Maria S. +4 more
core +3 more sources
Advanced Healthcare Materials, EarlyView.This work presents a novel, dynamically perfused, configurable microfluidic system for epidermis‐only (E and full‐thickness skin (FT SoC) growth, emulating human skin structure and barrier function. Upon TiO2 nanoparticle exposure, the system reveals compromised barrier integrity, reduced metabolic activity, increased permeability, and chemokine‐driven
Samantha Costa +7 more
wiley +1 more source
Revista Brasileira de Plantas Medicinais, 2010 A espécie Jatropha gossypiifolia L. (Euphorbiaceae), popularmente conhecida como pião-roxo, entre tantos outros nomes, é um bom exemplo do tênue limiar que separa o efeito terapêutico do tóxico.
S.R. Mariz +3 more
doaj +1 more source
Harvesting the Promise of AOPs: An assessment and recommendations [PDF]
, 2018 The Adverse Outcome Pathway (AOP) concept is a knowledge assembly and communication tool to facilitate the transparent translation of mechanistic information into outcomes meaningful to the regulatory assessment of chemicals.
Ankley, Gerald T. +8 more
core +4 more sources
Advanced Healthcare Materials, EarlyView.A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger +7 more
wiley +1 more source
Application of high-content analysis in food toxicology
Zhongguo shipin weisheng zazhiHigh content analysis combines automated microscopy and quantitative image analysis to visualize in vitro models for multi-parameter analysis， which has the advantages of high efficiency， rapidity and multi-targeting， and it has been applied in the field
QIANG Yuwei, YANG Miao, LI Yufeng
doaj +1 more source