Results 71 to 80 of about 791,172 (411)

Green Toxicology: a strategy for sustainable chemical and material development

Environmental Sciences Europe, 2017
Green Toxicology refers to the application of predictive toxicology in the sustainable development and production of new less harmful materials and chemicals, subsequently reducing waste and exposure.
Sarah E. Crawford, Thomas Hartung, Henner Hollert, Björn Mathes, Bennard van Ravenzwaay, Thomas Steger-Hartmann, Christoph Studer, Harald F. Krug   +7 more
doaj   +1 more source

Statistical evaluation of in-vivo bioassays in regulatory toxicology considering males and females [PDF]

arXiv, 2020
The separate evaluation for males and females is the recent standard in in-vivo toxicology for dose or treatment effects using Dunnett tests. The alternative pre-test for sex-by-treatment interaction is problematic. Here a joint test is proposed considering the two sex-specific and the pooled Dunnett-type comparisons.
arxiv  

Synthetic cannabinoid use in a case series of patients with psychosis presenting to acute psychiatric settings : Clinical presentation and management issues [PDF]

, 2018
Background: Novel Psychoactive Substances (NPS) are a heterogeneous class of synthetic molecules including synthetic cannabinoid receptor agonists (SCRAs). Psychosis is associated with SCRAs use.
Bonaccorso, Stefania, Ducci, Giuseppe, Ferracuti, Stefano, Jamal, Leila, Metastasio, Antonio, Ricciardi, Angelo, Rujully, Naasir Ud Dinn, Schifano, Fabrizio, Stewart, Neil, Theleritis, Christos   +9 more
core   +2 more sources

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

Arthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp, Anne Horne, Borislav Mihov, Jill Drake, Janine Haslett, Peter Chapman, Daniel F. B. Wright, Christopher Frampton, Nicola Dalbeth   +8 more
wiley   +1 more source

Point Process Modeling of Drug Overdoses with Heterogeneous and Missing Data [PDF]

, 2020
Opioid overdose rates have increased in the United States over the past decade and reflect a major public health crisis. Modeling and prediction of drug and opioid hotspots, where a high percentage of events fall in a small percentage of space-time, could help better focus limited social and health services.
arxiv   +1 more source

Bioresorbable and Wireless Rechargeable Implanted Na‐ion Battery for Temporary Medical Devices

Advanced Functional Materials, EarlyView.
An all‐solid‐state bioresorbable Na‐ion battery is developed, composed entirely of bio‐eliminable materials. In vivo and ex vivo tests confirmed harmless disintegration of this implanted battery. Lifetime of the implanted battery can be precisely controlled by adjusting the dissolvable encapsulation layer's thickness.
Vedi Kuyil Azhagan Muniraj, Bincy Lathakumary Vijayan, Hussien Hammoud, Roger Delattre, Marc Ramuz, Eve Djenizian, Eleonora Vandini, Daniela Giuliani, Thierry Djenizian   +8 more
wiley   +1 more source

Scientometric Analysis of Toxicology in Asia Pacific Region: Signs of Growth [PDF]

Asia Pacific Journal of Medical Toxicology, 2014
Background: In recent decades, the science of toxicology in Asia Pacific (AP) region has been expanding. In this study, the productivity of the science of toxicology in the timeframe of the years 1996 to 2013 in AP region was evaluated and was compared ...
Reza Afshari
doaj  

Proteomic Comparison of the Cytotoxicology of Two Diastereomers of Citreamicin Reveals Differentially Activation of NF-κB Pathway

Frontiers in Marine Science, 2020
Citreamicin ε is a group of antitumor compounds produced by Streptomyces species. Cytotoxicology study of two diastereomers, citreamicin ε A and B, showed different apoptotic effects on PtK2 cells with IC50 (half-maximal inhibitory concentration) values ...
Ling-Li Liu, Ling-Li Liu, Jin Sun, Ying Xu, Li-Sheng He, Chandramouli Kondethimmanahalli, Pei-Yuan Qian   +6 more
doaj   +1 more source

Note on PI and Szeged indices [PDF]

Mathematical and Computer Modelling 52 (2010) 1570-1576, 2011
In theoretical chemistry molecular structure descriptors are used for modeling physico-chemical, pharmacological, toxicologic, biological and other properties of chemical compounds. In this paper we study distance-based graph invariants and present some improved and corrected sharp inequalities for PI, vertex PI, Szeged and edge Szeged topological ...
arxiv   +1 more source

H2O2‐Generating Advanced Nanomaterials for Cancer Treatment

Advanced Functional Materials, EarlyView.
H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie, Samin Abbaszadeh, Kik Marais, Vahideh Nosrati‐Siahmazgi, Saman Rezaei, Bo Xiao, Kamal Dua, Hélder A. Santos, Mohammad‐Ali Shahbazi   +8 more
wiley   +1 more source