Results 51 to 60 of about 388,698 (305)

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

The digital evolution in toxicology: pioneering computational education for emerging challenges

BMC Medical Education
The educational landscape of toxicology is increasingly integrating computational methodologies due to ethical concerns about animal testing and advancements in biotechnological and data analysis tools.
Jin Wang, Jianxiang Li
doaj   +1 more source

Non‐Additive Criteria Assessment in Sustainability Evaluation of High Entropy Alloys: A Toxicity‐Weighted Framework

Advanced Engineering Materials, EarlyView.
Sustainability assessment requires methodologies that appropriately distinguish between additive and non‐additive material properties. A toxicity‐weighted scoring system is developed and applied that accounts for the disproportionate influence of highly toxic constituents through nonlinear weighting functions, providing more realistic estimates than ...
Seth Mehalic, Oladele A. Ogunseitan, Julie M. Schoenung   +2 more
wiley   +1 more source

A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin

Frontiers in Pharmacology, 2022
Graphical ...
Shivkanya Fuloria, Jyoti Mehta, Aditi Chandel, Mahendran Sekar, Nur Najihah Izzati Mat Rani, M. Yasmin Begum, Vetriselvan Subramaniyan, Kumarappan Chidambaram, Lakshmi Thangavelu, Rusli Nordin, Yuan Seng Wu, Kathiresan V. Sathasivam, Pei Teng Lum, Dhanalekshmi Unnikrishnan Meenakshi, Vinoth Kumarasamy, Vinoth Kumarasamy, Abul Kalam Azad, Neeraj Kumar Fuloria, Neeraj Kumar Fuloria   +18 more
doaj   +1 more source

Wearable Smart Patches on Sustainable Chitosan With Reversible Microbial Growth‐Inhibitory Properties

Advanced Functional Materials, EarlyView.
ABSTRACT Chitosan, a polysaccharide upcycled from biowaste, has long promised sustainable, biocompatible, and antimicrobial films and devices, an appeal reinforced by its recent regulatory recognition, with several chitosan‐based antibacterial dressings gaining clearance through the Food and Drug Administration's 510(k) pathway.
Jacopo Nicoletti, Kubra Kocak, Andrea Michel, Enrico Cavarzerani, Ali Raza, Petr Rohzin, Nouha Loudhaief, Saimir Frroku, Nicolò Baldovin, Hazrat Bilal, Alvise Perosa, Maurizio Selva, Flavio Rizzolio, Luca Sbuelz, Sabrina Tamburini, Domenico De Fazio, Giovanni Antonio Salvatore   +16 more
wiley   +1 more source

Advancing SafeWax, A Bio‐Inspired Superhydrophobic Coating, Toward Sustainable and Climate‐Resilient Crop Protection

Advanced Functional Materials, EarlyView.
This study advances SafeWax, a bio‐inspired, fatty‐acids‐based superhydrophobic coating, by identifying an agriculturally compliant solvent and revealing how solvent‐controlled Fatty acid crystallization governs the coating's microscopic structure and performance.
Niv Ben‐Arie, Iryna Polishchuk, Franziska Tauber, Coralie Schneider, Elena Prudnikov, Alessia Calora, Silvia Milita, Simona Fermani, Mireia Alejandra Ibanez Revert, Ilaria Filippetti, Claudio Ratti, Matthias Kellermeier, Markus Rueckel, Boaz Pokroy   +13 more
wiley   +1 more source

Possibilidades terapêuticas e risco toxicológico de Jatropha gossypiifolia L.: uma revisão narrativa Therapeutic possibilities and toxicological risk of Jatropha gossypiifolia L.: a narrative review

Revista Brasileira de Plantas Medicinais, 2010
A espécie Jatropha gossypiifolia L. (Euphorbiaceae), popularmente conhecida como pião-roxo, entre tantos outros nomes, é um bom exemplo do tênue limiar que separa o efeito terapêutico do tóxico.
S.R. Mariz, A.C.R. Borges, M.F.F. Melo-Diniz, I.A. Medeiros   +3 more
doaj   +1 more source

The Toxicology Investigators Consortium Case Registry-the 2018 Annual Report. [PDF]

, 2019
The Toxicology Investigators Consortium (ToxIC) Registry was established by the American College of Medical Toxicology (ACMT) in 2010. The Registry collects data from participating sites with the agreement that all bedside medical toxicology consultation
Meadors, K., Scoccimarro, A., Greene, S. C., Porter, L., Kang, A. Min, Campleman, Sharan L., Chenoweth, J. A., Warrick, B. J., Shah, K. R., Spyres, M., McKay, C. A., Beauchamp, G. A., McKeever, R. G., Ganetsky, M., Cannon, R. D., Hendrickson, R. G., Mullins, M. E., Carey, J. L., Nelson, M. E., Moore, K., Riley, Brad D., Weiss, S., Fisher, E., Harding, S. A., Hoyte, C., Yanta, J., Farrugia, Lynn A., On behalf of the Toxicology Investigators Consortium (ToxIC) Study Group, Wiegand, Timothy, Judge, B. S., Liss, D. B., Wolk, B. J., Wax, Paul M., Fox, L. M., Kerns, W. P., Seifert, S. A., Kao, Louise, Kim, T., Calello, Diane P., Griswold, M. K., Schwarz, E. S., Pizon, Anthony, Jacob, J., Koons, A., Gorodetsky, R., Kazzi, Z., Tortora, L., Ford, J. B., Boyle, K. L., Marino, R., Riley, B. D., Spyres, Meghan B., Smolinske, S. C., Brent, Jeffery, Levine, M., Shafer, S., Schult, R., Beuhler, M. C., Colby, D. K., Nacca, N., Eisenga, B. H., Carpenter, J., Leikin, J. B., Li, Shao, Santos, C., Vearrier, D. J., Horowitz, B. Z., Spyres, Meghan B, Campleman, Sharan L, Riley, Brad D, Calello, Diane P, Toxicology Investigators Consortium (ToxIC) Study Group, Farrugia, Lynn A, Amaducci, Alexandra, DO, Kang, A Min, Wax, Paul M   +75 more
core   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Plant Secondary Metabolites Modulate Insect Behavior-Steps Toward Addiction?

Frontiers in Physiology, 2018
Plants produce a diversity of secondary metabolites (PSMs) that serve as defense compounds against herbivores and microorganisms. In addition, some PSMs attract animals for pollination and seed dispersal.
Michael Wink
doaj   +1 more source