Results 71 to 80 of about 650,384 (309)
In vitro 3D skin culture and its sustainability in toxicology: a narrative review
Artificial Cells, Nanomedicine, and BiotechnologyIn current toxicological research, 2D cell cultures and animal models are well- accepted and commonly employed methods. However, these approaches have many drawbacks and are distant from the actual environment in human.
Syafira Masri +5 more
doaj +1 more source
Developmental toxicity of combined ethylbenzene and methylethylketone administered by inhalation to rats [PDF]
, 2006 Pregnant Sprague–Dawley rats were exposed to ethylbenzene (EB; 0, 250, or 1000 ppm) and methylethylketone (MEK; 0, 1000, or 3000 ppm), alone and in combination, by inhalation, for 6 h/day, during days 6–20 of gestation.
Bourges-Abella, Nathalie +6 more
core +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen +9 more
wiley +1 more source
Application of high-content analysis in food toxicology
Zhongguo shipin weisheng zazhiHigh content analysis combines automated microscopy and quantitative image analysis to visualize in vitro models for multi-parameter analysis， which has the advantages of high efficiency， rapidity and multi-targeting， and it has been applied in the field
QIANG Yuwei, YANG Miao, LI Yufeng
doaj +1 more source
Pesticide Mixture Poisoning: A Case Report
Arab Journal of Forensic Sciences & Forensic Medicine, 2018 Acute pesticide poisoning is a reported as major health problem worldwide and are reported mostly in cases of suicides and cases of unintentional poisoning are less in number. A significant number of cases are encountered in forensic science laboratories
Atul Bajaj +3 more
doaj +1 more source
Environmental Toxicology: The legacy of Silent Spring [PDF]
, 2004 The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, London, on 12 March 2002. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2004.©The Trustee of the Wellcome
Christie, DA, Tansey, EM
core
Building Shared Experience to Advance Practical Application of Pathway-Based Toxicology: Liver Toxicity Mode-of-Action [PDF]
, 2014 Summary The Human Toxicology Project Consortium (HTPC) was created to accelerate implementation of the science and policies required to achieve a pathway-based foundation for toxicology as articulated in the 2007 National Research Council report on ...
ANDERSEN Melvin E. +20 more
core +1 more source
Computational Toxicology [PDF]
Chemical Research in Toxicology, 2020 Nicole C. Kleinstreuer +2 more
openaire +3 more sources
Advanced Materials, EarlyView.A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee +8 more
wiley +1 more source