Results 41 to 50 of about 271,521 (268)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Arab Scientific Working Group for Forensic Toxicology (ASWGFT): Guidelines for Method Validation in Forensic Toxicology

open access: yesArab Journal of Forensic Sciences & Forensic Medicine, 2017
Reliable results and valid analytical data are an essential requirement for proper interpretation of forensic toxicology cases, especially when evaluating scientific studies and daily routine work, and when presenting any toxicological findings as ...
Abdulsallam A. Bakdash   +2 more
doaj   +1 more source

Public health and public law issues for the toxicological risk assessment of chemical mixtures

open access: yesPublic Health and Toxicology, 2021
Humans are simultaneously exposed to a near-infinite number of substances of both nutritional and toxicological interest. While traditional risk assessment has been based on the evaluation of effects of single substances, real-life exposure is ...
Silvio Roberto Vinceti   +1 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Interdisciplinary curriculum reform in toxicology and environmental health education: a case study from the University of Alcalá.

open access: yesRevista Española de Educación Médica
Toxicology plays a critical role in safeguarding public health and the environment, yet its visibility and integration within higher education curricula in Europe have declined over recent decades.
Antonio Peña-Fernández
doaj   +1 more source

Receptor‐Free Identification of Toxic Gases Enabled by Hygroscopic Aqueous Salt Films

open access: yesAdvanced Functional Materials, EarlyView.
Water as a gas sensor coating sounds impossible—until it stops evaporating. Here, hygroscopic salt solutions (LiCl, LiBr, H3PO4) form non‐drying aqueous films on CNT chemiresistors under ambient air. Gases partition into these liquid layers, sometimes transforming into water, and generate salt‐specific resistance fingerprints across a four‐channel ...
Seongwoo Lee   +5 more
wiley   +1 more source

Scientometric Analysis of Toxicology in Asia Pacific Region: Signs of Growth [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2014
Background: In recent decades, the science of toxicology in Asia Pacific (AP) region has been expanding. In this study, the productivity of the science of toxicology in the timeframe of the years 1996 to 2013 in AP region was evaluated and was compared ...
Reza Afshari
doaj  

Toxicology: An Overview [PDF]

open access: yesAAOHN Journal, 1986
With the discovery of new “toxins.” the onus is not only on the manufacturer but also on the user This means fully evaluating the health and safety effects of the substances produced and used As health care professionals, we must continue to increase our knowledge and skills In order to maintain a healthy and safe work environment.
openaire   +2 more sources

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

open access: yesAdvanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández   +14 more
wiley   +1 more source

The digital evolution in toxicology: pioneering computational education for emerging challenges

open access: yesBMC Medical Education
The educational landscape of toxicology is increasingly integrating computational methodologies due to ethical concerns about animal testing and advancements in biotechnological and data analysis tools.
Jin Wang, Jianxiang Li
doaj   +1 more source

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