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Predicting clinical outcome ofEscherichia coliO157:H7 infections using explainable Machine Learning
Paganini JA +7 more
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Toxins: Bacterial and Marine Toxins
Clinics in Laboratory Medicine, 2006The term toxin refers in a specific way to a toxic substance of biologic origin; that is, a true toxin is a poison produced by a living organism. The purpose of this article is to review some of the most potentially dangerous toxins of concern today. Mechanisms of action, routes of exposure, diagnostic tools, and treatment recommendations are addressed.
Matthew Salzman +2 more
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Anesthesiology Clinics of North America, 2006
Exposures to toxins are prevalent, frequently complicate surgical emergencies, and impact critical care. A fundamental understanding of pathophysiologic principles and management strategies is essential for the anesthesiologist frequently responsible for the acute care of patients who have toxicologic exposures. Given their pervasiveness and ability to
John E, Sather, Hossam, Tantawy
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Exposures to toxins are prevalent, frequently complicate surgical emergencies, and impact critical care. A fundamental understanding of pathophysiologic principles and management strategies is essential for the anesthesiologist frequently responsible for the acute care of patients who have toxicologic exposures. Given their pervasiveness and ability to
John E, Sather, Hossam, Tantawy
openaire +2 more sources
Toxicon, 2011
Muscarinic toxins isolated from the venom of Dendroaspis snakes may interact with a high affinity, large selectivity and various functional properties with muscarinic receptors. Therefore, these toxins are invaluable tools for studying the physiological role, molecular functioning and structural organization of the five subtypes of these G-Protein ...
Servent, Denis +5 more
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Muscarinic toxins isolated from the venom of Dendroaspis snakes may interact with a high affinity, large selectivity and various functional properties with muscarinic receptors. Therefore, these toxins are invaluable tools for studying the physiological role, molecular functioning and structural organization of the five subtypes of these G-Protein ...
Servent, Denis +5 more
openaire +4 more sources
Trends in Microbiology, 2001
Researchers from Harvard Medical School have identified mutants of the anthrax toxin that could be used in the development of a therapeutic vaccine, as reported in Science. Rats injected with mutant protective antigen and a normally lethal dose of the anthrax toxin survived, suggesting that the mutant antigen could be useful as both a vaccine and an ...
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Researchers from Harvard Medical School have identified mutants of the anthrax toxin that could be used in the development of a therapeutic vaccine, as reported in Science. Rats injected with mutant protective antigen and a normally lethal dose of the anthrax toxin survived, suggesting that the mutant antigen could be useful as both a vaccine and an ...
openaire +2 more sources
Clinics in Geriatric Medicine, 2011
This article addresses physiologic organ system and cellular mechanisms of common toxic exposure in the elderly population. Air pollution, tobacco, alcohol, heat, cold, water pollution, medications, herbals,radiation, and other chemicals are discussed.
Asma B. Jafri +2 more
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This article addresses physiologic organ system and cellular mechanisms of common toxic exposure in the elderly population. Air pollution, tobacco, alcohol, heat, cold, water pollution, medications, herbals,radiation, and other chemicals are discussed.
Asma B. Jafri +2 more
openaire +3 more sources
Cyanobacterial toxins and toxin production
Phycologia, 1996Abstract Several cyanobacteria species commonly forming mass occurrences (blooms) in fresh, brackish and marine waters produce toxins. They have caused death of animals all over the world and may be a health hazard for humans. The toxins are classified, according to the target of their toxic action, as hepatotoxins, neurotoxins and dermatotoxins.
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Hormone, lectin and toxin-toxin conjugates
1988In order to better understand the relative importance of the A and B chains of diphtheria toxin and ricin, chimeras or hybrid toxins have been constructed with diphtheria toxin subunits and ricin subunits coupled to a number of different binding moieties.
Ronald G. Wiley, Thomas N. Oeltmann
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