Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Advanced Biology, EarlyView.Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez +3 more
wiley +1 more source
Optimization of modified bentonite mycotoxin binders for enhanced adsorption efficiency under simulated gastric and intestinal conditions. [PDF]
Sci RepFeizy J +5 more
europepmc +1 more source
THE TREATMENT OF INOPERABLE MALIGNANT TUMORS WITH THE TOXINS OF ERYSIPELAS AND BACILLUS PRODIGIOSUS [PDF]
, 1895 NULL AUTHOR_ID
openalex +1 more source
Advanced Biology, EarlyView.A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso +5 more
wiley +1 more source
Dual Signal Enhancement by Magnetic Separation and Split Aptamer for Ultrasensitive T-2 Toxin Detection. [PDF]
MoleculesYan Z, Zhu P, Zhou C, Kong D, Ye H.
europepmc +1 more source
Bradycardia of central origin produced by injections of tetanus toxin into the vagus nerve
, 1949 N Ambache, O. C. J. Lippold
openalex +2 more sources
A Method for the Production of Staphylococcus Toxin and Toxoid [PDF]
, 1935 George F. Leonard, August Holm
openalex +1 more source
Advanced Biology, EarlyView.The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali +5 more
wiley +1 more source
THE DICK TEST AND ACTIVE IMMUNIZATION WITH SCARLET FEVER STREPTOCOCCUS TOXIN
, 1924 Abraham Zingher
openalex +2 more sources
Antimicrobial Titanium–Copper Alloys: The Role of Microstructure in Arc‐Melted Compositions
Advanced Engineering Materials, EarlyView.Copper‐containing titanium alloys show promise in combating orthopedic implant infections. This study explores the influence of heat treatment on Ti‐11.5Cu and Ti‐33Cu alloys, revealing that larger Ti2Cu precipitates (≈5 μm) enhance antimicrobial efficacy through increased surface contact. Results suggest contact sterilization is the primary mechanism,
Daisy Rabbitt +5 more
wiley +1 more source