Results 311 to 320 of about 987,804 (362)
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Seafood toxins

Clinical Reviews in Allergy, 1993
We have presented in some detail the more common clinical syndromes produced by the ingestion of natural seafood toxins, and touched on those that could be of interest to the international traveler and to the sport fisherman. For the practicing allergist, knowledge of this wide array of clinical syndromes of toxicity is of paramount importance for the ...
A M, Saavedra-Delgado, D D, Metcalfe
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Streptococcal Toxins

Clinical Infectious Diseases, 1983
Few of the cellular components of group A streptococci appear to be directly toxic for animals or humans. Some preparations of M protein produce an immunotoxic effect on human platelets and neutrophils. Cell wall fragments produce a chronic multinodular inflammatory lesion of dermal connective tissue.
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Botulinum Toxin

Critical Care Clinics, 2005
Botulinum toxin is regarded as the most lethal substance known. It is estimated that the human LD50 for inhalation botulism is 1 to 3 nanograms of toxin/kilogram body mass. Although only three cases of inhalational botulism have been described, an understanding of the pathophysiology of food-borne outbreaks, wound botulism, and infant botulism, and ...
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Shiga toxins

Toxicon, 2001
Shiga toxin and Shiga-like toxins belong to the group of protein toxins which have a moiety that binds to the cell surface and another enzymatically active moiety that after entry into the cytosol inhibits protein synthesis enzymatically. The toxins can also cause apoptosis by mechanisms that may be different from the effect on the protein synthesis ...
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Botulinum Toxins

2020
Clostridium botulinum is an anaerobic, gram-positive bacterium that secretes an extremely large neurotoxic molecule (900 kDa), which produces food poisoning or botulism. It is now also used in medicine to treat diseases according to Paracelsus's paradigm that the difference between a poison and a drug lies in the dose.
Signorini, Massimo   +5 more
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Uremic toxins.

Kidney international. Supplement, 1988
It is the purpose of this paper to review our present knowledge about uremic toxicity, with a special emphasis on the methods that have been used to try to resolve this problem. More and more, sophisticated methods become available for the study of uremic toxicity.
Ringoir, S.M.G.   +2 more
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Intestinal toxins

Current Opinion in Gastroenterology, 1999
The application of molecular techniques to the study of bacterial pathogenesis has made possible discoveries that are changing the way scientists view the bacterium-host interaction. Today, research on the molecular basis of the pathogenesis of infective diarrheal diseases of necessity transcends established boundaries between cell biology ...
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Fighting toxins with toxins

Trends in Microbiology, 2001
Researchers from Harvard Medical School have identified mutants of the anthrax toxin that could be used in the development of a therapeutic vaccine, as reported in Science. Rats injected with mutant protective antigen and a normally lethal dose of the anthrax toxin survived, suggesting that the mutant antigen could be useful as both a vaccine and an ...
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Anthrax Toxin

Critical Reviews in Microbiology, 2001
Anthrax is primarily a disease of herbivores caused by gram-positive, aerobic, spore-forming Bacillus anthracis. Humans are accidental hosts through the food of animal origin and animal products. Anthrax is prevelant in most parts of the globe, and cases of anthrax have been reported from almost every country.
R, Bhatnagar, S, Batra
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Anthrax toxins

Cellular and Molecular Life Sciences (CMLS), 1999
Though its lethal effects were ascribed to an exotoxin almost half a century ago, the pathogenesis of anthrax has yet to be satisfactorily explained. Subsequent work has led to the molecular identification and enzymatic characterization of three proteins that constitute two anthrax toxins.
N S, Duesbery, G F, Vande Woude
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