Results 151 to 160 of about 595,436 (374)
Toxin Inactivation in Toxin/Antitoxin Systems
, 2019 Toxin/antitoxin (TA) systems are used primarily to inhibit phage, reduce metabolic activity during stress, and maintain genetic elements. Given the extreme toxicity of some of the toxins of these TA systems, we were curious how the cell silences toxins, if the antitoxin is inactivated or when toxins are obtained without antitoxins via horizontal gene ...
Laura Fernandez-Garcia +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
A simple mathematical model for assessment of anti-toxin antibodies [PDF]
arXiv, 2011 The toxins associated with infectious diseases are potential targets for inhibitors which have the potential for prophylactic or therapeutic use. Many antibodies have been generated for this purpose, and the objective of this study was to develop a simple mathematical model that may be used to evaluate the potential protective effect of antibodies ...
arxiv
ToxinsScorpion envenomation poses a global public health issue, with an estimated 1,500,000 cases worldwide annually resulting in 2600 deaths. North Africa, particularly Morocco, experiences severe envenomations, mainly attributed to Androctonus mauretanicus ...
Bouchra Darkaoui +8 more
doaj +1 more source
, 2009 Lethal intoxications of animals dwelling in aquatic habitats are recurrently observed with blooms of cyanobacteria. The latter produces two types of toxins : cytotoxins & biotoxins and a few antibiotics (allelopaths) such as acutiphycins, indolcarbazoles, tantazoles, tolytoxins etc.
Garg, HK, Garg, Jaya
openaire +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Numerical and analytical approaches to an advection-diffusion problem at small Reynolds number and large Péclet number [PDF]
arXiv, 2016 Obtaining a detailed understanding of the physical interactions between a cell and its environment often requires information about the flow of fluid surrounding the cell. Cells must be able to effectively absorb and discard material in order to survive. Strategies for nutrient acquisition and toxin disposal, which have been evolutionarily selected for
arxiv
The Treatment of Malignant Tumours by the Toxins of the Streptococcus Erysipelatis and Bacillus Prodigiosus [PDF]
, 1895 J. R. SWAIN
openalex +1 more source