Environmental and Regulatory Control of RTX Toxins in Gram-Negative Pathogens. [PDF]
Jamali H, Pereira T, Dozois CM.
europepmc +1 more source
Serotonin as a biomarker of toxin-induced Parkinsonism [PDF]
Anna Marie Buchanan +12 more
openalex +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Proteinaceous Toxins in the Mucus and Proboscis of the Ribbon Worm <i>Cephalothrix</i> cf. <i>simula</i> (Palaeonemertea: Nemertea). [PDF]
Kuznetsov VG +3 more
europepmc +1 more source
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Optimization of Ibuprofen Route and Dosage to Enhance Protein-Bound Uremic Toxin Clearance During Hemodialysis. [PDF]
Escudero-Saiz VJ +10 more
europepmc +1 more source
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Reply to Peigneur et al. The Helix Ring Peptide U11 from the Venom of the Ant, <i>Tetramorium bicarinatum</i>, Acts as a Putative Pore-Forming Toxin, Not a New Kv1.3 Channel Blocker. Comment on "Boy et al. A New Kv1.3 Channel Blocker from the Venom of the Ant <i>Tetramorium bicarinatum</i>. <i>Toxins</i> 2025, <i>17</i>, 379". [PDF]
Boy G +8 more
europepmc +1 more source
The role of lipid metabolism in neuronal senescence
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source

