Results 21 to 30 of about 113,320 (229)

Regulation of arginine transport by GCN2 eIF2 kinase is important for replication of the intracellular parasite Toxoplasma gondii [PDF]

open access: yes, 2019
Toxoplasma gondii is a prevalent protozoan parasite that can infect any nucleated cell but cannot replicate outside of its host cell. Toxoplasma is auxotrophic for several nutrients including arginine, tryptophan, and purines, which it must acquire from ...
Amin, Parth H.   +3 more
core   +2 more sources

Role of Toxoplasma gondii IgG Avidity Testing in Discriminating between Acute and Chronic Toxoplasmosis in Pregnancy

open access: yesJournal of Clinical Microbiology, 2020
Risk of mother-to-child transmission of Toxoplasma gondii during pregnancy is much greater in women who are exposed to primary T. gondii infection (toxoplasmosis) after conception compared to those who were exposed to the infection before conception ...
Aref Teimouri   +3 more
semanticscholar   +1 more source

The Interplay of Host Autophagy and Eukaryotic Pathogens

open access: yesFrontiers in Cell and Developmental Biology, 2018
For intracellular pathogens, host cells provide a replicative niche, but are also armed with innate defense mechanisms to combat the intruder. Co-evolution of host and pathogens has produced a complex interplay of host-pathogen interactions during ...
Robert J. Evans   +2 more
doaj   +1 more source

Serological Study of IgG and IgM Antibodies to Cytomegalovirus and Toxoplasma Infections in Pregnant Women in Zakho City, Kurdistan Region, Iraq [PDF]

open access: yesWomen’s Health Bulletin, 2019
Background: Toxoplasma gondii and Cytomegalovirus (CMV) can cause a range of diseases in pregnant women and may lead to adverse fetal outcomes. Therefore, the detection of these infections is necessary during pregnancy.
Ibrahim Naqid   +2 more
doaj   +1 more source

Serotyping of Toxoplasma gondii Infection Using Peptide Membrane Arrays. [PDF]

open access: yes, 2019
The intracellular parasite Toxoplasma gondii can cause chronic infections in most warm-blooded animals, including humans. In the USA, strains belonging to four different Toxoplasma clonal lineages (types 1, 2, 3, and 12) are commonly isolated, whereas ...
Arranz-Solís, David   +6 more
core   +1 more source

C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo [version 1; peer review: 2 approved]

open access: yesWellcome Open Research, 2019
Background: Infections cause the production of inflammatory cytokines such as Interferon gamma (IFNγ). IFNγ in turn prompts the upregulation of a range of host defence proteins including members of the family of guanylate binding proteins (Gbps).
Barbara Clough   +7 more
doaj   +1 more source

Development of Human Toxo IgG ELISA Kit, and False-Positivity of Latex Agglutination Test for the Diagnosis of Toxoplasmosis

open access: yesPathogens, 2021
Toxoplasma gondii is an intracellular zoonotic parasite that causes infection in a wide range of warm-blooded animals and humans. The main aim of this study was to assess the diagnostic value of the recombinant SAG1 antigen (rSAG1) for T.
Sarfraz-ur-Rahman   +4 more
doaj   +1 more source

Murine Gbp1 and Gbp2 are ubiquitinated independent of Toxoplasma gondii infection

open access: yesBMC Research Notes, 2018
Objective The intracellular parasite Toxoplasma gondii can invade any nucleated cell residing inside a parasitophorous vacuole (PV). Upon infection, the cytokine interferon gamma (IFNγ) is produced and elicits host defence mechanisms able to recognise ...
Vesela Encheva   +3 more
doaj   +1 more source

Interplay between cross sectional analysis of risk factors associated with Toxoplasma gondii infection in pregnant women and their domestic cats

open access: yesFrontiers in Veterinary Science, 2023
Toxoplasmosis is a global zoonotic disease caused by Toxoplasma gondii (T. gondii). The primary aim of this study was to identify hygienic and cat management practices that could affect the occurrence of T.
Eman A. A. Hassanen   +10 more
doaj   +1 more source

Serological and Molecular Survey of Toxoplasma gondii Infection in Hemodialysis Patients with Chronic Renal Disease in Zahedan, Iran [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2021
Background: Toxoplasma gondii is one of the most prevalent zoonotic opportunistic parasitic infections in the world. The aim of this study was to examine chronic and acute toxoplasmosis molecularly and serologically in Hemodialysis patients.Methods: A ...
Hadi Mirahmadi   +5 more
doaj   +1 more source

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