Results 111 to 120 of about 143,360 (244)

In Vivo Biotinylation of the Toxoplasma Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and Pathogenesis. [PDF]

open access: yes, 2016
UnlabelledToxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite secretes an array of dense granule proteins (GRAs) into ...
Bell, Hannah N   +7 more
core   +2 more sources

Homozygous Pathogenic Variant in Elongation Factor‐Like 1 (EFL1) as a Causal Factor in Shwachman‐Diamond Syndrome 2 in a Palestinian Child, With Distinct Ocular Manifestations

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
We report a Palestinian female infant with a homozygous pathogenic EFL1 variant (c.3284G>A; p.Arg1095Gln) causing Shwachman–Diamond syndrome type 2 (SDS2). Beyond the classical features of pancytopenia, exocrine pancreatic insufficiency, and growth failure, the patient showed previously unreported ocular manifestations—stage 2–3 retinopathy of ...
Ibrahim Taha   +13 more
wiley   +1 more source

Human toxoplasmosis: a systematic review for genetic diversity of Toxoplasma gondii in clinical samples

open access: yesEpidemiology and Infection, 2018
Toxoplasma gondii (T. gondii) as an obligate intracellular protozoan with a worldwide distribution can infect virtually all warm-blooded animals and humans. This study aims to provide a summary of the available data on genotypes of T.
S. Hosseini   +9 more
semanticscholar   +1 more source

Quality control of protein import into mammalian mitochondria

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Mitochondrial function depends on the continuous import of hundreds of nuclear‐encoded proteins. Targeting and translocation of mitochondrial proteins is a multistep process that is inherently vulnerable to defects in cytosolic quality control systems as well as perturbations in mitochondrial protein import machinery and organelle function ...
Madeleine Goldstein   +2 more
wiley   +1 more source

Prevalence of Toxoplasma gondii IgG Antibodies and Associated Risk Factors in Psychiatric Patients from Western Romania: A Cross-Sectional Study

open access: yesMicroorganisms
Infection with the coccidian parasite Toxoplasma gondii was associated with an increased risk of several mental disorders. We conducted a case–control study of 464 consecutive psychiatric patients and assessed the prevalence of IgG antibodies against T ...
Sebastian Grada   +5 more
doaj   +1 more source

Characterization of exosomes derived from Toxoplasma gondii and their functions in modulating immune responses

open access: yesInternational Journal of Nanomedicine, 2018
Introduction Exosomes are nanograde membrane-bound vesicles secreted from most cell types through the fusion of multivesicular bodies with plasma membranes.
Yawen Li   +9 more
semanticscholar   +1 more source

Metabolic interactions between Toxoplasma gondii and its host

open access: yesF1000Research, 2018
Toxoplasma gondii is an obligate intracellular parasite belonging to the phylum Apicomplexa that infects all warm-blooded animals, including humans. T.
M. Blume, F. Seeber
semanticscholar   +1 more source

Successful Management of Septic Splenitis in an Abyssinian Cat

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 3.5‐year‐old female neutered Abyssinian with pyrexia of unknown origin and splenomegaly was diagnosed with septic splenitis. Complete resolution of clinical signs followed splenectomy and antibiotic treatment with pradofloxacin. Septic splenitis, although uncommon, should be considered as a differential diagnosis in patients with splenomegaly and ...
Martina Vecín Sancho   +10 more
wiley   +1 more source

Patogenia, respuesta inmune y bioseguridad, elementos a considerar para el trabajo con Toxoplasma gondii

open access: yesCorreo Científico Médico, 2012
Un gran volumen de artículos científicos sobre patogenia del Toxoplasma gondii como agente causal de la Toxoplasmosis y respuesta inmune del hombre frente a este parásito fueron revisados.
Rolando Sánchez Artigas   +4 more
doaj  

Seroprevalence of Toxoplasma gondii infection and associated risk factors in Huicholes in Mexico

open access: yesParasites & Vectors, 2014
Background Very little is known about the seroepidemiology of Toxoplasma gondii infection in ethnic groups in Mexico. Huicholes are an indigenous ethnic group living in a remote mountainous region in Mexico.
Cosme Alvarado-Esquivel   +10 more
doaj   +1 more source

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