Results 91 to 100 of about 82,548 (220)
ABSTRACT Introduction Wild boars and domestic pigs can act as intermediate hosts for two Sarcocystis species: Sarcocystis miescheriana and the zoonotic Sarcocystis suihominis. Humans become infected with S. suihominis by eating raw or undercooked meat. Herein we investigated the occurrence of Sarcocystis spp.
Weronika Korpysa‐Dzirba +12 more
wiley +1 more source
Seroprevalence of Toxoplasma gondii infection and associated risk factors in Huicholes in Mexico
Background Very little is known about the seroepidemiology of Toxoplasma gondii infection in ethnic groups in Mexico. Huicholes are an indigenous ethnic group living in a remote mountainous region in Mexico.
Cosme Alvarado-Esquivel +10 more
doaj +1 more source
The Plasmodium berghei Ca(2+)/H(+) exchanger, PbCAX, is essential for tolerance to environmental Ca(2+) during sexual development. [PDF]
Ca(2+) contributes to a myriad of important cellular processes in all organisms, including the apicomplexans, Plasmodium and Toxoplasma. Due to its varied and essential roles, free Ca(2+) is tightly regulated by complex mechanisms.
Staines, Henry M. +64 more
core +1 more source
Adaptive Immunity in Marsupials
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol +2 more
wiley +1 more source
Un gran volumen de artículos científicos sobre patogenia del Toxoplasma gondii como agente causal de la Toxoplasmosis y respuesta inmune del hombre frente a este parásito fueron revisados.
Rolando Sánchez Artigas +4 more
doaj
Incidence of symptomatic toxoplasma eye disease: aetiology and public health implications. [PDF]
Ocular disease is the commonest disabling consequence of toxoplasma infection. Incidence and lifetime risk of ocular symptoms were determined by ascertaining affected patients in a population-based, active reporting study involving ophthalmologists ...
Murray, PI +24 more
core +1 more source
Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood +7 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
A One Health molecular investigation of Cryptosporidium across humans, animals and the environment revealed the circulation of multiple zoonotic species and subtypes within a shared ecosystem. Molecular characterisation and phylogenetic analysis highlighted transmission at the human–animal–environment interface. The findings emphasise the importance of
Majed H Wakid +6 more
wiley +1 more source
Glancing at the role of Toxoplasma gondii in neuro-oncology: from risk factor to therapeutic target
Background Cancer is a leading cause of morbidity and mortality, with brain tumors posing significant challenges due to their site and complexity. Therefore, exploring tumor pathogenesis and the discovery of novel therapeutic agents have drawn attention ...
Maha M. Eissa +2 more
doaj +1 more source

