Results 41 to 50 of about 13,597 (224)

Toxoplasmosis of Goat and Sheep in Java

open access: yes, 2008
Toxoplasmosis is a parasitic disease, caused by Toxoplasma gondii attacking goat, sheep, and wild animals. This disease is zoonosis and widely distributed in many districts of Java and as a zoonotic disease. Cat is the definitive host of T. gondii, while
Iskandar, Tolibin
core   +1 more source

Experimental Porcine Toxoplasma gondii Infection as a Representative Model for Human Toxoplasmosis

open access: yesMediators of Inflammation, 2017
Porcine infections are currently not the state-of-the-art model to study human diseases. Nevertheless, the course of human and porcine toxoplasmosis is much more comparable than that of human and murine toxoplasmosis.
Julia Nau   +8 more
doaj   +1 more source

Humane Endpoints in Swiss Webster Mice Infected with Toxoplasma gondii RH Strain

open access: yesAnimals
The highly virulent Toxoplasma gondii RH strain is maintained through successive passages in mice, but there is still a lack of studies that refine these procedures from a 3Rs perspective, where humanitarian ideals aim to minimize the stress, pain, or ...
Igor Falco Arruda   +7 more
doaj   +1 more source

Berberine alleviates pyroptosis of retinal ganglion cells in diabetic retinopathy by regulating AKT1, JUN, and STAT3

open access: yesIbrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li   +7 more
wiley   +1 more source

Vaccines against toxoplasma gondii : challenges and opportunities [PDF]

open access: yes, 2009
Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects.
Craig W Roberts   +10 more
core   +1 more source

Spread of Toxoplasma gondii among animals and humans in Northern Italy: A retrospective analysis in a One-Health framework

open access: yesFood and Waterborne Parasitology, 2023
Toxoplasmosis occurs worldwide and is considered one of the most important food-borne parasitic zoonoses. The consumption of undercooked meat containing viable tissue cysts and ingestion of environmental oocyst are the most important sources of infection.
F.M. Dini   +9 more
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Spatial epidemiology of Toxoplasma gondii infection in goats in Serbia

open access: yesGeospatial Health, 2014
A major risk factor for Toxoplasma gondii infection is consumption of undercooked meat. Increasing demand for goat meat is likely to promote the role of this animal for human toxoplasmosis.
Vitomir Djokić   +6 more
doaj   +1 more source

“For three of my four miscarriages I was at work…” Experiences of miscarriage, infertility and assisted fertility in veterinary workplaces

open access: yesVeterinary Record, EarlyView.
Abstract Background Miscarriage, infertility and assisted fertility (MIAF) can profoundly impact physical and mental health. The aims of this study were to investigate how veterinary professionals’ work environments and employers impacted their experiences of MIAF and to identify how workplace experiences of MIAF could be improved.
Jenny Stavisky   +3 more
wiley   +1 more source

A Review About Toxoplasmosis on Animals and Humans

open access: yes, 2014
Toxoplasmosis, a zoonotic infectious disease caused by Toxoplasma gondii, is reported to be endemic throughout most of the Indonesian archipelago . The prevalence rates of 24-61% in goats, 10-40% in cats, 28% in pigs, 43% in sheep, 36% in cattle, 27% in ...
Iskandar, Tolibin
core   +1 more source

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