FDA Approval of the First-Ever PROTAC: Vepdegestrant (ARV-471) Marks a New Era in Targeted Protein Degradation. [PDF]
Kumar A, Ali S, Shen Q, Zhou J.
europepmc +1 more source
The effects of environmental regulations on performance of firms with heterogeneous resilience
Abstract This study explores the impacts of environmental regulations on performance of heterogeneous firms through both theoretical modelling and empirical analysis. It further examines the role of firm resilience in moderating these impacts. We develop a dynamic general equilibrium model predicting that a stricter environmental regulation increases ...
Liang Chen +2 more
wiley +1 more source
Trimetallic Single-Atom Alloys: Active Site Synergy or Most Reactive Atom Dominance? The Case of RhPtCu(111). [PDF]
Lal V, H Sykes EC.
europepmc +1 more source
A guide to transcriptional cyclin‐dependent kinases in cancer
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin +2 more
wiley +1 more source
Using the theory of positive disintegration's 'dynamisms' to gauge retrospective suicide lived experience. [PDF]
Schläppy ML +4 more
europepmc +1 more source
Brand Equity and Debt Diversification
ABSTRACT This study examines how brand equity influences the diversity of firms’ debt structures. We propose that brand equity, by signaling larger and more stable future cash flows and greater product market awareness, alters the fundamental trade‐offs that drive optimal debt type diversity.
David C. Mauer +2 more
wiley +1 more source
Insights into Active Sites of Dehydrogenation-Condensation-Dehydration Steps in Ethanol-to-1,3-Butadiene Conversion over Tailored MgO-SiO<sub>2</sub> Catalysts. [PDF]
Zhang Z +5 more
europepmc +1 more source
Carotid artery dissection linked to intermittent apnoeic swimming: A case–control study
Abstract Internal carotid artery (ICA) dissection is a rare and potentially devastating cause of cerebral ischaemia, initiated by an intimal tear or rupture of the vasa vasorum, that can lead to an intraluminal thrombus, vascular stenosis, occlusion, or dissecting aneurysm formation.
Damian M. Bailey +14 more
wiley +1 more source
Origin of sulfur allotropes on the carbonaceous asteroid Ryugu and implications to the sulfur chemistry in the interstellar medium. [PDF]
McAnally M +5 more
europepmc +1 more source

