Results 51 to 60 of about 4,646 (139)

Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval [PDF]

, 2020
Sudden cardiac death is responsible for half of all deaths from cardiovascular disease. The analysis of the electrophysiological substrate for arrhythmias is crucial for optimal risk stratification.
Young, WJ, Orini, M, Ramirez, J, Lambiase, PD, Tinker, A, Munroe, PB, van Duijvenboden, S   +6 more
core   +1 more source

Data_Sheet_1_Predictive Value of Tpeak – Tend Indices for Adverse Outcomes in Acquired QT Prolongation: A Meta-Analysis.PDF

, 2018
Background: Acquired QT interval prolongation has been linked with malignant ventricular arrhythmias, such as torsade de pointes, in turn predisposing to sudden cardiac death. Increased dispersion of repolarization has been identified as a pro-arrhythmic
Martin C. S. Wong (288769), Matthew T. V. Chan (295579), Adrian Baranchuk (5234165), Lei Meng (1394350), Gan-Xin Yan (5710613), Tong Liu (107783), Cheuk W. Wong (5710610), Gary Tse (1805596), William K. K. Wu (96084), George Bazoukis (5246576), Mengqi Gong (1727662), Konstantinos P. Letsas (3818068)   +11 more
core   +1 more source

No Association Between T-peak to T-end Interval on the Resting ECG and Long-Term Incidence of Ventricular Arrhythmias Triggering ICD Interventions

Frontiers in Physiology, 2020
Background and ObjectivesPotential of using the T-peak to T-end (TpTe) interval as an electrocardiographic parameter reflecting the transmural dispersion of ventricular repolarization (TDR) to identify patients (pts.) with higher risk of malignant ...
Peter Michalek, Sasha Benjamin Hatahet, Martin Svetlosak, Peter Margitfalvi, Iveta Waczulikova, Sebastian Trnovec, Allan Böhm, Allan Böhm, Ondrej Benacka, Ondrej Benacka, Robert Hatala, Robert Hatala   +11 more
doaj   +1 more source

Relationship between subclinical hyperthyroidism and ventricular repolarization markers

Sakarya Tıp Dergisi, 2022
Objective: To evaluate repolarization defects and arrhythmogenic predisposition through ventricular repolarization markers in patients with subclinical hyperthyroidism (sHT).
Ercan Aydın, Kadem Arslan, Emre Yılmaz
doaj   +1 more source

Relationship Between Morning Hypertension and T-Peak to T-End Interval in Patients with Suspected Coronary Heart Disease

Cardiovascular Innovations and Applications, 2017
Objective: To investigate the relationship between morning hypertension (MH) and T-peak to T-end interval (Tp-e interval) in patients with suspected coronary heart disease. Methods: Patients with typical symptoms of coronary heart disease were examined
Lili Wei, Datun Qi, Yong’en Shi, Chuanyu Gao, Weili Liu   +4 more
doaj   +1 more source

Optimizing the predictive validity of NIRS kinetic profiles to predict aerobic capacity from a resting skeletal muscle occlusion test

Experimental Physiology, Volume 111, Issue 3, Page 738-750, 1 March 2026.
Abstract Measuring and monitoring individual cardiorespiratory fitness through a valid and accessible non‐exhaustive surrogate is required. Techniques measuring haemodynamics have shown promise, and this study aimed to optimize the predictive validity of these approaches alongside developing predictive equations.
Heru Syarli Lesmana, Kyohei Marume, Justin S. Lawley   +2 more
wiley   +1 more source

Effects of moxifloxacin on the proarrhythmic surrogate markers in healthy Filipino subjects: Exposure-response modeling using ECG data of thorough QT/QTc study

Journal of Pharmacological Sciences, 2018
Effects of moxifloxacin on QTc as well as proarrhythmic surrogate markers including J-Tpeakc, Tpeak-Tend and short-term variability (STV) of repolarization were examined by using both standard E14 time-based evaluation and exposure-response modeling. The
Suchitra Matsukura, Yuji Nakamura, Kiyotaka Hoshiai, Takashi Hayashi, Tadashi Koga, Ai Goto, Koki Chiba, Nur Jaharat Lubna, Mihoko Hagiwara-Nagasawa, Hiroko Izumi-Nakaseko, Kentaro Ando, Atsuhiko T. Naito, Atsushi Sugiyama   +12 more
doaj   +1 more source

Suppression of premature ventricular complexes with the PDE5 inhibitor sildenafil: First clinical experience

Experimental Physiology, Volume 111, Issue 3, Page 625-631, 1 March 2026.
Abstract The phosphodiesterase‐5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug‐induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing ‘R‐on‐T’ ventricular tachycardia.
David C. Hutchings, Christopher P. Denton, Luigi Venetucci, Andrew W. Trafford   +3 more
wiley   +1 more source

Heritability of Tpeak-Tend Interval and T-Wave Amplitude

, 2011
Background— Tpeak-Tend interval (TpTe) and T-wave amplitude (Tamp) carry diagnostic and prognostic information regarding cardiac morbidity and mortality. Heart rate and QT interval are known to be heritable traits.
Esben Vedel-Larsen, Kyvik, Kirsten O; id_orcid, Vedel-Larsen, Esben, Budtz-Jørgensen, Esben, Kanters, Jørgen K., Jørgen K. Kanters, Christian Haarmark, Kirsten O. Kyvik, Kyvik, Kirsten O, Esben Budtz-Jørgensen, Haarmark, Christian   +10 more
core   +1 more source

The relationship between length of stay in intensive care unit and Tpeak‐Tend and Tpeak‐Tend/QTc ratio in COVID 19 patients with acute coronary syndrome

, 2022
Background Patients with coronavirus disease 2019 (COVID‐19) can develop cardiac injury resulting in cardiac arrhythmias, myocarditis, and acute coronary syndrome (ACS).
Emine Altuntas, Sükrü Cetın, Bayram Bagırtan, Kanber Ocal Karabay, Filiz Celebı   +4 more
core   +1 more source