Results 51 to 60 of about 1,584,226 (169)

QT interval and repolarization dispersion changes during the administration of hydroxychloroquine/chloroquine with/without azithromycin in early COVID 19 pandemic: A prospective observational study from two academic hospitals in Indonesia

Journal of Arrhythmia, 2021
Background Hydroxychloroquine/chloroquine (HCQ/CQ) treatment for COVID‐19 was associated with QT interval prolongation and arrhythmia risks. This study aimed to investigate QTc interval and ventricular repolarization dispersion changes, as markers of ...
Rizki A. Gumilang, Siswanto, Vita Y. Anggraeni, Ika Trisnawati, Eko Budiono, Anggoro B. Hartopo   +5 more
doaj   +1 more source

The Cardiovascular Effects of a Meal: J-Tpeak and Tpeak -Tend Assessment and Further Insights Into the Physiological Effects. [PDF]

, 2019
Meal intake leads to a significant and prolonged increase in cardiac output to supply the splanchnic vasculature. A meal is associated with sympathetic activation of the cardiovascular system, and food ingestion is correlated with an increase in heart ...
Jörg Täubel, Camm, AJ, Ferber, G, Fernandes, S, Van Langenhoven, L, Van Langenhoven, Leen, Jørgen K. Kanters, A. John Camm, Del Bianco, T, Teresa del Bianco, Graff, Claus, Kanters, JK, Graff, C, Sara Fernandes, Leen Van Langenhoven, Ferber, Georg, Kanters, Jørgen K, Georg Ferber, Camm, A John, Täubel, J, Täubel, Jörg, Dilshat Djumanov, Djumanov, D, Graff, Claus; id_orcid, Djumanov, Dilshat, Kanters, Jørgen K., Fernandes, Sara, Del Bianco, Teresa, Claus Graff   +28 more
core   +1 more source

Tpeak-Tend, Tpeak-Tend dispersion and Tpeak-Tend/QT in children and its relationship with clinical variables

, 2019
Aim: To characterize the Tpeak-Tend, the Tpeak-Tend dispersion and Tpeak-Tend/QT in children and its relationship with clinical variables. Methods: Cross-sectional study in 126 children between 9 and 12 years of the Camilo Cienfuegos School in Santa ...
Elibet Chávez-González, Carmona Puerta, Raimundo, Raimundo Carmona-Puerta, González Rodríguez, Emilio Francisco, Emilio Francisco González-Rodríguez, Yaniel Castro-Torres, Castro Torres, Yaniel, Chávez González, Elibet   +7 more
core   +1 more source

Deep Learning Improves Robustness of Voxelwise Kinetic Modeling for Hyperpolarized Carbon‐13 MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To evaluate whether deep learning improves the robustness of voxelwise kinetic parameter estimation from hyperpolarized (HP) 13C MRI compared with nonlinear least‐squares (NLLS) fitting. Methods A hybrid neural network (NN) was trained on synthetic pyruvate/lactate time courses generated from an open‐system two‐compartment HP 13C ...
Kofi Deh, Yeona Kang, Tsang‐Wei Tu, Rania Jones, Curtiland Deville, Rao Khan   +5 more
wiley   +1 more source

Evaluation of QT dispersion and T-peak to T-end interval in patients with early-stage sarcoidosis

Revista Portuguesa de Cardiologia, 2017
Introduction and Aim: Sarcoidosis increases inhomogeneity in ventricular repolarization due to the presence of sarcoid granuloma, which significantly correlates with ventricular fibrillation. Various studies have suggested that the interval from the peak
Hacı Ahmet Kasapkara, Ayşegül Şentürk, Emine Bilen, Hüseyin Ayhan, Bilge Duran Karaduman, Zeynep Şeyma Turinay, Murat Can Güney, Tahir Durmaz, Telat Keleş, Engin Bozkurt   +9 more
doaj   +1 more source

Effect of Mesoporous Bioactive Glass on the Morphology and Thermal Properties of PLA‐Based Biocomposites for Bone Tissue Engineering

Polymer Engineering &Science, EarlyView.
Schematic overview of the preparation and characterization of PLA‐based biocomposites containing mesoporous bioactive glass, highlighting the relationship between particle morphology, composite properties, and their potential for bone regeneration. ABSTRACT The present study proposes the development of a potential biocomposite for bone regeneration by ...
Bruna Segat, Luis Guilherme Silva Rosa, Felippe Migliato Marega, Luiz Antonio Pessan, Lidiane Cristina Costa, Daniela Becker   +5 more
wiley   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Torsade de pointes induced by intravenous amiodarone therapy accompanied by marked augmentation of the transmural dispersion of repolarization in a patient with tachycardia‐induced‐cardiomyopathy

Annals of Noninvasive Electrocardiology, 2021
We report a 77‐year‐old human on renal dialysis for end‐stage renal disease with heart failure and atrial fibrillation (AF) complicated by a high ventricular frequency. The underlying disease was thought as tachycardia‐induced‐cardiomyopathy. Intravenous
Ryo Yonai, Mihoko Kawabata, Shingo Maeda, Tomoyuki Kawashima, Yasuhide Tsuda, Takashi Nakasone, Hiroki Nakane, Kenzo Hirao   +7 more
doaj   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

Relationship between transmural dispersion of repolarization, Tpeak-Tend interval, and ventricular arrhythmias: reply [PDF]

Europace, 2007
We thank Dr Swenne and his colleagues for their interest in our manuscript.1 Transmural dispersion of repolarization (TDR) in the heart has been linked to a variety of arrhythmic manifestations.2 Three electrophysiologically distinct cell types have been identified in the ventricular myocardium: endocardial, epicardial, and M cells.
L. Santangelo, E. Ammendola, V. Russo, C. Cavallaro, F. Vecchione, S. Garofalo, A. D'Onofrio, R. Calabro   +7 more
openaire   +1 more source