Results 31 to 40 of about 69,255 (308)

A manutenção produtiva total na indústria extrativa mineral: a metodologia TPM como suporte de mudanças [PDF]

open access: yes, 2001
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro TecnológicoA efetiva participação do Brasil, no moderno processo tecnológico, disseminado através da globalização, principalmente após a queda das barreiras alfandegárias, tem ...
Souza, José Carlos
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The ameliorative effect of gallic acid and/or Lasix on topiramate-induced renal impairment in male rats

open access: yesOpen Veterinary Journal
Background: Topiramate (TPM) is commonly used for migraine prophylaxis; nonetheless, it is linked to nephrotoxicity, which mostly results from oxidative stress and inflammatory mechanisms.
Rana Ramadan   +3 more
doaj   +1 more source

Methods and Conditions for Achieving Continuous Improvement of Processes [PDF]

open access: yesRevista de Management Comparat International, 2010
In the early twentieth century, the Taylor model improved, in a spectacular maner the efficiency of the production processes. This allowed obtaining high productivity by low-skilled workers, but used in large number in the execution of production ...
Florica BADEA   +2 more
doaj  

TPM implementation in automotive component manufacturing companies to analyze efficiency injection machine

open access: yesJournal of Applied Research on Industrial Engineering, 2019
The development of motorcycle industry in Indonesia is quite rapid. The mode of transportation is a favorite the people of Indonesia, especially in industrial area.
Supriyati, Humiras Purba
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Enhancing production line performance through an integrated OEE-FMEA model: a case study at Hoa Sen Nghe An

open access: yesTạp chí Khoa học và Công nghệ
This study introduces an integrated methodology, combining Overall Equipment Effectiveness (OEE) and Failure Mode and Effects Analysis (FMEA), to enhance operational performance within the NOF1 production line at Hoa Sen Nghe An Co., Ltd.
Vu T. Hanh, Phan H. Hoang
doaj   +1 more source

Total productive maintenance: an in-depth review with a focus on overall equipment effectiveness measurement [PDF]

open access: yesInternational Journal of Research in Industrial Engineering
This paper will explore the objectives and advantages associated with the implementation of Total Productive Maintenance (TPM). It will specifically delve into the calculation of Overall Equipment Effectiveness (OEE) within a steel company based in ...
Joyeshree Biswas
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

The effective maintenance strategy on the example of a company from the manufacturing industry

open access: yesNowoczesne Systemy Zarządzania
Research objectives and hypothesis/research questions Analysis of the production system in terms of the effectiveness of the maintenance strategy ear.
Natalia Zawierucha
doaj   +1 more source

Home - About - Disclaimer - Privacy