Psychotic symptoms due to topiramate
Topiramate is an antiepileptic drug prescribed in the treatment of numerous psychiatric disorders and in epilepsy. Topiramate exerts its antiepileptic effect through different mechanisms, such as by the blockage of sodium channels, increasing GABAergic
Gülay Oğuz +3 more
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Add-on Effect of Levetiracetam on Cognitive Activity of Carbamazepine and Topiramate Treated Healthy Rats [PDF]
Background: Many antiseizure drugs are used for non-epileptic indications like bipolar disorder, anxiety, neuropathic pain, prophylaxis of migraine, etc.
Priti Dhande +3 more
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Topiramate is an anti-epileptic drug that is commonly prescribed not just to prevent seizures but also migraine headaches, with over 8 million prescriptions dispensed annually.
Syed K Rafi +8 more
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Agranulocytosis Associated with Topiramate: A Case Report and Review of Published Cases
A 41-year-old female presented to the hospital with sore throat and shortness of breath. She was hypoxic with an oxygen saturation of 87% in room air. Physical examination revealed swollen uvula with exudates.
Saroj Lohani +3 more
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Comparison between baclofen and topiramate in alcohol dependence: A prospective study
Introduction: Baclofen and topiramate are GABAergic drugs, and both have been recommended for the treatment of alcohol dependence as anticraving agent. Several studies have demonstrated the effect of baclofen and topiramate as anticraving, but none has ...
Nimmi A Jose +3 more
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Topiramate and Pregabalin in Lumbar Radicular Pain. Is Topiramate a better option?
Objective: To compare the efficacy of two anticonvulsant drugs topiramate and pregabalin on lumbar radicular pain and to find out whether topiramate is a better option or not. Study design: Experimental study.
Asim Ishfaq +2 more
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A trial of topiramate for patients with hereditary spinocerebellar ataxia
In an open pilot trial, six patients with various hereditary forms of spinocerebellar ataxia (SCA) were assigned to topiramate (50 mg/day) for 24 weeks. Four patients completed the protocol without adverse events.
Shiroh Miura +5 more
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Topiramate for smoking cessation: Systematic review and meta-analysis
Introduction Topiramate is an antiepileptic drug that has been used for many labeled and off-labeled indications. It may be useful in reducing withdrawal symptoms of various addictive agents such as alcohol, cocaine, cannabis and smoking.
Nesma Lotfy +2 more
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Probable topiramate-induced diarrhea in a 2-month-old breast-fed child — A case report
An infant developed a severe condition of recurrent and persistent watery diarrhea at 40 days of age. The child had been partially breast-fed, and the mother used topiramate for epilepsy.
Tone Westergren +4 more
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Topiramate treatment is neuroprotective and reduces oligodendrocyte loss after cervical spinal cord injury. [PDF]
Excess glutamate release and associated neurotoxicity contributes to cell death after spinal cord injury (SCI). Indeed, delayed administration of glutamate receptor antagonists after SCI in rodents improves tissue sparing and functional recovery. Despite
John C Gensel +3 more
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