New players in the preventive treatment of migraine. [PDF]
Migraine is a common, chronic disorder of the brain causing much disability, as well as personal, familial and societal impact. Several oral preventive agents are available in different countries for the prevention of migraine, but none have performed ...
Mitsikostas, Dimos D, Rapoport, Alan M
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Comparison between baclofen and topiramate in alcohol dependence: A prospective study
Introduction: Baclofen and topiramate are GABAergic drugs, and both have been recommended for the treatment of alcohol dependence as anticraving agent. Several studies have demonstrated the effect of baclofen and topiramate as anticraving, but none has ...
Nimmi A Jose +3 more
doaj +1 more source
Case Reports : Topiramate, a concealed cause of severe metabolic acidosis [PDF]
Severe metabolic acidosis is common among critically ill patients, and topiramate is a rare cause that may fail recognition. We report a lady with acute encephalopathy who had severe non-anion gap metabolic acidosis that served as the clue leading to ...
Lovinger, Daniel +3 more
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Agranulocytosis Associated with Topiramate: A Case Report and Review of Published Cases
A 41-year-old female presented to the hospital with sore throat and shortness of breath. She was hypoxic with an oxygen saturation of 87% in room air. Physical examination revealed swollen uvula with exudates.
Saroj Lohani +3 more
doaj +1 more source
Add-on Effect of Levetiracetam on Cognitive Activity of Carbamazepine and Topiramate Treated Healthy Rats [PDF]
Background: Many antiseizure drugs are used for non-epileptic indications like bipolar disorder, anxiety, neuropathic pain, prophylaxis of migraine, etc.
Priti Dhande +3 more
doaj +1 more source
European Guidelines for Obesity Management in Adults [PDF]
Obesity is a chronic metabolic disease characterised by an increase of body fat stores. It is a gateway to ill health, and it has become one of the leading causes of disability and death, affecting not only adults but also children and adolescents ...
Busetto, Luca +6 more
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Psychotic symptoms due to topiramate
Topiramate is an antiepileptic drug prescribed in the treatment of numerous psychiatric disorders and in epilepsy. Topiramate exerts its antiepileptic effect through different mechanisms, such as by the blockage of sodium channels, increasing GABAergic
Gülay Oğuz +3 more
doaj +1 more source
Topiramate for smoking cessation: Systematic review and meta-analysis
Introduction Topiramate is an antiepileptic drug that has been used for many labeled and off-labeled indications. It may be useful in reducing withdrawal symptoms of various addictive agents such as alcohol, cocaine, cannabis and smoking.
Nesma Lotfy +2 more
doaj +1 more source
Efficacy of Multi-Modal Migraine Prophylaxis Therapy on Hyperacusis Patients. [PDF]
ObjectivesTo evaluate the efficacy of a multi-modal migraine prophylaxis therapy for patients with hyperacusis.MethodsIn a prospective cohort, patients with hyperacusis were treated with a multi-modal step-wise migraine prophylactic regimen ...
Abouzari, Mehdi +7 more
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Caenorhabditis elegans as a model system to identify therapeutics for alcohol use disorders [PDF]
Alcohol use disorders (AUDs) cause serious problems in society and few effective treatments are available. Caenorhabditis elegans (C. elegans) is an excellent invertebrate model to study the neurobiological basis of human behavior with a conserved, fully
Bell, Richard L. +6 more
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