Results 21 to 30 of about 28,018 (262)
Brain Sciences, 2023 Objectives: To investigate the effect of tiapride and topiramate on patients with Tourette syndrome (TS). Methods: This retrospective analysis included 126 children diagnosed with TS at Children’s Hospital of Chongqing Medical University from 2019 to ...
Xuanzi Zhou +4 more
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A new method for the preparation of pure topiramate with a micron particle size [PDF]
Journal of Particle Science and Technology, 2017 Crude topiramate was prepared from the reaction between diacetonefructopyranose, sulfuric diamide, and 2-picoline. During a controlled processing the presence of Triton-X-100, crude topiramate in a methanol-water solvent, was converted to pure micron ...
Bahman Hassanzadeh +1 more
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BMC Ophthalmology, 2021 Background Topiramate (TPM) is a drug commonly used by neurophysicians and psychiatrists for a plethora of indications. Topiramate has been reported to induce acute angle closure glaucoma as an adverse effect.
Mudit Tyagi +5 more
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Toxicology Reports, 2022 Background: Topiramate is an anticonvulsant from sulfamate-substituted monosaccharides that is increasingly used to treat migraines. Serious topiramate intoxications have been described.
Tim Schutte +4 more
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Topiramate modulates trigeminal pain processing in thalamo-cortical networks in humans after single dose administration. [PDF]
PLoS ONE, 2017 Migraine is the sixth most common cause of disability in the world. Preventive migraine treatment is used to reduce frequency, severity and duration of attacks and therefore lightens the burden on the patients' quality of life and reduces disability ...
Julia M Hebestreit, Arne May
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Pharmaceuticals, 2023 Cadmium is an environmental toxicant that instigates cognitive deficits with excessive glutamate excitatory neuroactivity in the brain. Topiramate, a glutamate receptor antagonist, has displayed favorable neuroprotection against epilepsy, cerebral ...
Hany H. Arab +9 more
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The Effects of Topiramate Applied to the Nucleus Accumbens Region on Morphine Withdrawal Syndrome [PDF]
, 2020 Aim:Nucleus accumbens, one of the nuclei of the basal ganglia, and dopamine, the neurotransmitter play a critical role in opioid dependence and withdrawal. In opioid withdrawal, the importance of neurotransmitters such as glutamate and gamma aminobutyric
Ramazan BAKAR +9 more
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Nephrolithiasis and Nephrocalcinosis From Topiramate Therapy in Children With Epilepsy
Kidney International Reports, 2018 Introduction: Adults treated with topiramate may develop nephrolithiasis, but its frequency in children on topiramate is unknown. Topiramate inhibits renal carbonic anhydrase, which can lead to renal tubular acidosis and hypercalciuria.
Sarah M. Barnett +4 more
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Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1998 ABSTRACT:In controlled clinical trials, topiramate (TopamaxR) has demonstrated efficacy in refractory patients with complex partial seizures and secondarily generalized tonic-clonic seizures. Approximately 45 percent of 534 patients had a ≥ 50 percent reduction in seizure frequency.
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Epilepsy Currents, 2008 Topiramate Monotherapy in Newly Diagnosed Epilepsy in Children and Adolescents. Glauser TA, Dlugos DJ, Dodson WE, Grinspan A, Wang S, Wu SC; EPMN-106/INT-28 Investigators. J Child Neurol 2007;22(6):693–699. A double-blind, dose-controlled study evaluated topiramate as monotherapy in 470 patients with newly diagnosed (3 months) epilepsy or epilepsy ...
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