Nephrolithiasis and Nephrocalcinosis From Topiramate Therapy in Children With Epilepsy
Introduction: Adults treated with topiramate may develop nephrolithiasis, but its frequency in children on topiramate is unknown. Topiramate inhibits renal carbonic anhydrase, which can lead to renal tubular acidosis and hypercalciuria.
Sarah M. Barnett +4 more
doaj +1 more source
Comparison between baclofen and topiramate in alcohol dependence: A prospective study
Introduction: Baclofen and topiramate are GABAergic drugs, and both have been recommended for the treatment of alcohol dependence as anticraving agent. Several studies have demonstrated the effect of baclofen and topiramate as anticraving, but none has ...
Nimmi A Jose +3 more
doaj +1 more source
Agranulocytosis Associated with Topiramate: A Case Report and Review of Published Cases
A 41-year-old female presented to the hospital with sore throat and shortness of breath. She was hypoxic with an oxygen saturation of 87% in room air. Physical examination revealed swollen uvula with exudates.
Saroj Lohani +3 more
doaj +1 more source
Topiramate for smoking cessation: Systematic review and meta-analysis
Introduction Topiramate is an antiepileptic drug that has been used for many labeled and off-labeled indications. It may be useful in reducing withdrawal symptoms of various addictive agents such as alcohol, cocaine, cannabis and smoking.
Nesma Lotfy +2 more
doaj +1 more source
Add-on Effect of Levetiracetam on Cognitive Activity of Carbamazepine and Topiramate Treated Healthy Rats [PDF]
Background: Many antiseizure drugs are used for non-epileptic indications like bipolar disorder, anxiety, neuropathic pain, prophylaxis of migraine, etc.
Priti Dhande +3 more
doaj +1 more source
Probable topiramate-induced diarrhea in a 2-month-old breast-fed child — A case report
An infant developed a severe condition of recurrent and persistent watery diarrhea at 40 days of age. The child had been partially breast-fed, and the mother used topiramate for epilepsy.
Tone Westergren +4 more
doaj +1 more source
A trial of topiramate for patients with hereditary spinocerebellar ataxia
In an open pilot trial, six patients with various hereditary forms of spinocerebellar ataxia (SCA) were assigned to topiramate (50 mg/day) for 24 weeks. Four patients completed the protocol without adverse events.
Shiroh Miura +5 more
doaj +1 more source
A case of Alice in Wonderland Syndrome associated with topiramate in a patient with vestibular migraine [PDF]
Introduction Alice in Wonderland Syndrome (AIWS) is an uncommon condition manifesting visual and somatosensory disturbances in which patients may perceive objects, including their own bodies, as larger or smaller than they are.
Wen X. Jiang +3 more
doaj +1 more source
Topiramate treatment is neuroprotective and reduces oligodendrocyte loss after cervical spinal cord injury. [PDF]
Excess glutamate release and associated neurotoxicity contributes to cell death after spinal cord injury (SCI). Indeed, delayed administration of glutamate receptor antagonists after SCI in rodents improves tissue sparing and functional recovery. Despite
John C Gensel +3 more
doaj +1 more source
Topiramate-induced Myopic Shift and Bilateral Secondary Angle-closure Glaucoma
In this case report, we discuss a 24-year-old female patient with diagnosis of epilepsy who developed myopia and acute bilateral angleclosure glaucoma after 7 days of treatment with topiramate.
Hatice Tarakçıoğlu +2 more
core +1 more source

