Results 41 to 50 of about 28,018 (262)

RARE SIDE EFFECT OF TOPIRAMATE - A CASE REPORT [PDF]

open access: yes, 2015
Topiramate (sulfamate-substituted monosaccharide) is a broad spectrum newer anti-convulsant. It is also used in prophylaxis of migraine, cluster headache, bipolar affective disorder, post traumatic stress disorder, post herpetic neuralgia, relapse ...
Mohan, Murali   +2 more
core   +1 more source

Economic evaluations of antiobesity medications: A systematic literature review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković   +5 more
wiley   +1 more source

GRIA2 Variant Associated With Paradoxical Response to Perampanel Expanding the Spectrum of GRIA2‐Related Epileptic Encephalopathy: Case Report and Literature Review

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction GRIA2 encodes the GluA2 ionotropic α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPA) receptor subunit. Pathogenic GRIA2 variants cause epilepsy, developmental delay, and neurobehavioral disorders. Characterizations of clinical features, including seizure types and their treatments, in patients with GRIA2‐related ...
Sai Srihitha Dommata   +9 more
wiley   +1 more source

Topiramate-induced angle closure glaucoma in a case of chronic migraine

open access: yesMedical Journal of Dr. D.Y. Patil University, 2017
Topiramate is an oral sulfamate medication used primarily for epilepsy and migraine. The tolerability profile with its lack of significant metabolic side effects makes it a favorable drug for patients with comorbid lifestyle illnesses. Topiramate-induced
V A Arun, Y S Sirohi, Yatharth Dixit
doaj   +1 more source

Erenumab versus topiramate: post hoc efficacy analysis from the HER-MES study

open access: yesThe Journal of Headache and Pain, 2022
Objective HER-MES was the first head-to-head, phase 4 trial to assess the tolerability and effectiveness of erenumab against standard of care treatment (topiramate). This post hoc analysis compared the efficacy of erenumab with topiramate in patients who
Marc Ehrlich   +4 more
doaj   +1 more source

Topiramate-Induced Suicidal Ideation and Olfactory Hallucinations: A Case Report

open access: yesReports, 2022
Antiepileptic drugs prescribed in the context of migraine have been reported to be potentially linked with an increased risk of suicidal ideation and behavior.
Alexandre Hudon, Stéphane Proulx
doaj   +1 more source

Topiramate improves neurovascular function, epidermal nerve fiber morphology, and metabolism in patients with type 2 diabetes mellitus

open access: yes, 2010
Amanda L Boyd, Patricia M Barlow, Gary L Pittenger, Kathryn F Simmons, Aaron I VinikDepartment of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA, USAPurpose: To assess the effects of topiramate on C-fiber function, nerve fiber morphology,
null Boyd, Boyd A
core   +1 more source

Obstructive Sleep Apnea in Children With Lennox‐Gastaut Syndrome: A Case Series

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Background Lennox–Gastaut syndrome (LGS) is a highly refractory epilepsy syndrome associated with poor sleep. Abnormal sleep can lower seizure threshold, yet a treatable cause of disordered sleep, obstructive sleep apnea (OSA), is understudied in children with LGS.
Gita Gupta   +5 more
wiley   +1 more source

A review of the efficacy and safety of extended-release topiramate in the adjunctive treatment for refractory partial-onset seizures

open access: yesTherapeutic Advances in Neurological Disorders, 2015
Topiramate has been widely utilized worldwide as an effective medication against partial- and generalized-onset seizures. Extended-release topiramate was developed to provide patients with the convenience of once-daily dosing and potentially improved ...
Steve S. Chung
doaj   +1 more source

Population‐Stratified Distributions of Post‐Mortem Blood Drug Concentrations: An Epidemiological Framework for Contextual Interpretation

open access: yesDrug Testing and Analysis, EarlyView.
Post‐mortem blood drug concentrations exhibit substantial overlap between deaths in which a drug was implicated and those in which it was not. Analysis of over 58,000 NPSUM cases demonstrates that demographic stratification does not resolve this uncertainty, reinforcing the need for contextual, evidence‐based interpretation rather than concentration ...
Thikra Algahtani   +6 more
wiley   +1 more source

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