Results 61 to 70 of about 28,018 (262)
Epileptic Disorders, EarlyView.Abstract Objective Current recommendations for prescribing combined oral contraceptives (COCs) to people with epilepsy are often conflicting, particularly for weak inducers of cytochrome P450 3A4. We aimed to critically review the literature and compare the antiseizure medication (ASM)‐induced changes in exposure to COC components.
Hagar Cohen +4 more
wiley +1 more source
Topiramate-induced modulation of hepatic molecular mechanisms: an aspect for its anti-insulin resistant effect. [PDF]
PLoS ONE, 2012 Topiramate is an antiepileptic drug known to ameliorate insulin resistance besides reducing body weight. Albeit liver plays a fundamental role in regulation of overall insulin resistance, yet the effect of topiramate on this organ is controversial and is
Hanan S El-Abhar, Mona F Schaalan
doaj +1 more source
Epileptic Disorders, EarlyView.Abstract Objective To compare the incidence of hostility‐ and aggression‐related adverse events in children with focal‐onset seizures (FOS), with or without focal to bilateral tonic–clonic seizures (FBTCS), receiving perampanel as monotherapy or in combination with other antiseizure medications (ASMs).
Yukitoshi Takahashi +5 more
wiley +1 more source
Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis
Epilepsia, EarlyView.Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, suggesting a role for oligogenic inheritance.
Sarah Duerinckx +192 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective A multi‐electrode array (MEA) is a powerful extracellular recording technique for long‐term monitoring of neuronal network activity. In recent years, MEA‐based assays have been applied increasingly to evaluate drug efficacy and neurotoxicity, including the assessment of anti‐seizure medications (ASMs). However, systematic comparisons
Griselda Marku +4 more
wiley +1 more source
HeliyonMorphine belongs to the class of opioids and is known for its potential to cause dependence and addiction, particularly with prolonged use. Due to the associated risks, caution must be taken when prescribing and limiting its clinical use.
Shabir Hussain +5 more
doaj +1 more source
Topiramate Induced Excessive Sialorrhea [PDF]
, 2015 It is well-known that drugs such as clozapine and lithium can cause sialorrhea. On the other hand, topiramate has not been reported to induce sialorrhea.
Dag, Ersel +2 more
core +1 more source
Altered cortical synchronization in photosensitive idiopathic generalized epilepsy
Epilepsia, EarlyView.Abstract Objective To characterize cortical excitability and synchronization dynamics in patients with idiopathic generalized epilepsy (IGE) and photosensitivity by assessing steady‐state visual evoked potentials (SSVEPs) elicited by intermittent photic stimulation.
Alessandro Benedetto +5 more
wiley +1 more source
Journal of Ardabil University of Medical Sciences, 2019 Background: Topiramate, is an oral sulfonamide medication that is increasingly used for treating headache. We report a rare case of bilateral myopia and acute, secondary angle closure glaucoma following use of topiramate.
Yousef Fekri, Habib Ojaghi
doaj
Narrative Review of Topiramate: Clinical Uses and Pharmacological Considerations
, 2023 Due to the diverse mechanisms of action of antiseizure drugs, there has been a rise in prescriptions of these drugs for non-epileptic pathologies. One drug that is now being used for a variety of conditions is topiramate.
Caroline P. Babin +13 more
core +1 more source