Results 81 to 90 of about 36,003 (284)
De novo TANC2 stop‐loss variant associated with developmental impairment and drug‐resistant epilepsy
Epileptic Disorders, EarlyView.
Matthew A. Hintermayer, Kenneth A. Myers
wiley +1 more source
Did the French pregnancy pictogram change antiseizure medication use during pregnancy?
Epilepsia, EarlyView.Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo +7 more
wiley +1 more source
HeliyonMorphine belongs to the class of opioids and is known for its potential to cause dependence and addiction, particularly with prolonged use. Due to the associated risks, caution must be taken when prescribing and limiting its clinical use.
Shabir Hussain +5 more
doaj +1 more source
Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome
Epilepsia, EarlyView.Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan +14 more
wiley +1 more source
Erenumab in chronic migraine: Patient-reported outcomes in a randomized double-blind study. [PDF]
, 2019 OBJECTIVE: To determine the effect of erenumab, a human monoclonal antibody targeting the calcitonin gene-related peptide receptor, on health-related quality of life (HRQoL), headache impact, and disability in patients with chronic migraine (CM). METHODS:
Cheng, Sunfa +10 more
core +1 more source
Preventive treatment of migraine [PDF]
, 2006 Migraine is a common episodic pain disorder, the treatment of which can be acute to stop an attack or preventive to reduce the frequency, duration or severity of attacks. Preventive treatment is used when attacks are frequent or disabling. Many different
Silberstein, Stephen
core +2 more sources
Epilepsia, EarlyView.Abstract Objective Inclusion and exclusion criteria of clinical trials for seizures aim to select representative participants with a high enough seizure frequency to evaluate the efficacy of treatment in a relatively short double‐blind period. To inform the selection of seizure frequency‐based inclusion criteria, we evaluated the association between ...
Wesley T. Kerr +5 more
wiley +1 more source
Short term outcomes of topiramate monotherapy as a first-line treatment in newly diagnosed West syndrome [PDF]
, 2011 PurposeTo investigate the efficacy of topiramate monotherapy in West syndrome prospectively.MethodsThe study population included 28 patients (15 male and 13 female children aged 2 to 18 months) diagnosed with West syndrome. After a 2-week baseline period
Gyu Min Lee +3 more
core +1 more source
Women with epilepsy: Evidence‐based counseling across the lifespan
Epilepsia, EarlyView.Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn +7 more
wiley +1 more source