Results 111 to 120 of about 8,384 (285)

The TUBA1B–G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin, Hechun Lin, Junming Yu, Chao Ge, Lin Mao, Saihua Zhang, Yizi Jin, Yunyu Wu, Taoyang Chen, Jinjun Li, Hong Li   +10 more
wiley   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Perceptions of Novice and Experienced Translators toward the Role of High-quality Translated Tourism Promotional Materials (TPMs) in Promoting the Tourism Industry in Saudi Arabia

مجلة العلوم التربوية والدراسات الإنسانية سلسلة الآداب والعلوم التربوية والإنسانية والتطبيقية
In today’s world, high-quality translated tourism promotional materials (TPMs) play a leading role in developing business sectors in general and the tourism sector in particular because TPMs are the most often used forms of media targeting actual ...
Ali Albashir Mohammed Alhaj
doaj   +1 more source

Parametric design and evaluation of TPMS-like cellular solids

, 2022
Triply periodic minimal surfaces (TPMS) present a starting point for designing infinitely many novel cellular solids, creating the need for a structured approach to their design and evaluation.
Mark Easton (18029899), Stuart Bateman (18027142), Martin Leary (18029377), Alistair Jones (8154501)   +3 more
core  

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Curvature modulation of TPMS-based lattices: from geometric design to enhanced mechanical responses

Virtual and Physical Prototyping
The performance optimisation of Triply Periodic Minimal Surfaces (TPMS) structures currently faces a critical bottleneck involving a transition from a density-driven to a geometry-driven paradigm.
Ruobing Liao, Zhi Guo, Jichao Liu, Zihong Mai, Xiangyu Ma, Mohd Zamir Pakhuruddin, Hang Zhang, Chengjun Luo, Liang Zhu, Kun Li, Huajun Cao   +10 more
doaj   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Trippla periodiska minimala ytor (TPMS-strukturer)för koldioxidinfångning: inverkan

In this study, the application of TPMS structures for the absorption and desorption of carbon dioxide in BECCS processes was investigated. The project focused on testing different TPMS geometries, produced using 3D printing, through laboratory ...
Rusetskaya, Volha
core   +2 more sources

Dynamic response-based isogeometric analysis of graphene platelets-reinforced functionally graded triply periodic minimal surface plates supported by Pasternak foundation

Alexandria Engineering Journal
Recent progress in additive manufacturing (AM) has transformed how complex bioinspired engineering structures are designed and produced. Nonetheless, these structures present substantial difficulties in mathematical modeling and computational analysis ...
Ngoc-Tu Do, Huu Trong Dang, Trung Thanh Tran, Nguyen Vinh Du, Quoc Hoa Pham   +4 more
doaj   +1 more source

Investigating Experimental and Computational Fluid Dynamics of 3D-Printed TPMS and Lattice Porous Structures

This study investigates the capillary performance and wetting behavior of SLA (Stereolithography) 3D-printed porous structures, focusing on TPMS (triply periodic minimal surfaces)-Gyroid, Octet, Diamond, and Isotruss lattice designs.
Kang, Guru Varun Penubarthi；Kishore Bhaskar Suresh Babu；Senthilkumar Sundararaj；Shung Wen
core   +1 more source