Results 111 to 120 of about 162,834 (322)

Correction: Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways

open access: yesPLoS ONE, 2015
Avian reovirus (ARV) protein p17 has been shown to regulate cell cycle and autophagy by activation of p53/PTEN pathway; nevertheless, it is still unclear how p53 and PTEN are activated by p17.
Wei‐Ru Huang   +5 more
semanticscholar   +1 more source

Activation of thromboxane A2 receptors mediates endothelial dysfunction in diabetic mice

open access: yesClinical and Experimental Hypertension, 2017
Background: Diabetes is one of high-risk factors for cardiovascular disease. Improvement of endothelial dysfunction in diabetes reduces vascular complications. However, the underlying mechanism needs to be uncovered. This study was conducted to elucidate
Xiaona Xie   +5 more
doaj   +1 more source

What to Make and How to Make It: Combining Machine Learning and Statistical Learning to Design New Materials

open access: yesAdvanced Intelligent Discovery, EarlyView.
Combining machine learning and probabilistic statistical learning is a powerful way to discover and design new materials. A variety of machine learning approaches can be used to identify promising candidates for target applications, and causal inference can help identify potential ways to make them a reality.
Jonathan Y. C. Ting, Amanda S. Barnard
wiley   +1 more source

Calcium Regulates the Activity and Structural Stability of Tpr, a Bacterial Calpain-like Peptidase*

open access: yesJournal of Biological Chemistry, 2015
Background: Calcium-activated, family C2 cysteine peptidases (calpains) are rare among prokaryotes, and none have been characterized. Results: Tpr peptidase from Porphyromonas gingivalis requires calcium for stability, autoprocessing, and activity ...
Dominika Staniec   +8 more
semanticscholar   +1 more source

Investigation on Measuring Total Peripheral Resistance of Human Body by Means of Reconstructed Impedance Cardiogram

open access: yesMATEC Web of Conferences, 2017
The purpose in this article is to investigate the measurement method and normal values of the total peripheral resistance (TPR) and total peripheral resistance index (TPRI) measured by the reconstructed impedance cardiogram (RICG).
Shi-jiang Kuang   +3 more
doaj   +1 more source

Artificial Intelligence‐Driven Insights into Electrospinning: Machine Learning Models to Predict Cotton‐Wool‐Like Structure of Electrospun Fibers

open access: yesAdvanced Intelligent Discovery, EarlyView.
Electrospinning allows the fabrication of fibrous 3D cotton‐wool‐like scaffolds for tissue engineering. Optimizing this process traditionally relies on trial‐and‐error approaches, and artificial intelligence (AI)‐based tools can support it, with the prediction of fiber properties. This work uses machine learning to classify and predict the structure of
Paolo D’Elia   +3 more
wiley   +1 more source

Truncation of the TPR domain of OGT alters substrate and glycosite selection

open access: yesAnalytical and Bioanalytical Chemistry, 2021
Daniel H. Ramirez   +4 more
semanticscholar   +1 more source

The Relationship between TRP (Total Physical Response) with Memory of Chinese Characters [PDF]

open access: yes, 2012
Chinese characters are considered by many people as one of the most difficult words to read. The purpose of this project is to exam if Total Physical Response (TPR) strategy improves non-native speakers’ memory of Chinese characters.
Feng, Shuyi
core   +2 more sources

Moduli of nodal curves on smooth surfaces of general type

open access: yes, 2001
In this paper we focus on the problem of computing the number of moduli of the so called Severi varieties (denoted by V(|D|, \delta)), which parametrize universal families of irreducible, \delta-nodal curves in a complete linear system |D|, on a smooth ...
Flamini, F.
core   +1 more source

Identification of Exhaled Volatile Organic Compounds Biomarkers for Lung Cancer Under Data‐Limited Conditions Using Data Augmentation and Multi‐View Feature Selection

open access: yesAdvanced Intelligent Discovery, EarlyView.
This work introduces a novel framework for identifying non‐small cell lung cancer biomarkers from hundreds of volatile organic compounds in breath, analyzed via gas chromatography‐mass spectrometry. This method integrates generative data augmentation and multi‐view feature selection, providing a stable and accurate solution for biomarker discovery in ...
Guancheng Ren   +10 more
wiley   +1 more source

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