Results 211 to 220 of about 162,834 (322)

A Hanks‐type bacterial kinase, PknS, directly phosphorylates the alternative sigma factor EcfK to promote resistance to protist predation

The FEBS Journal, EarlyView.
The Xanthomonas citri Hanks‐type kinase PknS autophosphorylates and directly phosphorylates the alternative sigma factor EcfK at five residues. Besides the conserved residue T51 in the σ2 domain, phosphorylation of a residue in the linker between σ2 and σ4 is critical for EcfK activation by promoting its interaction with a positively charged pocket in ...
Lídia dos Passos Lima, Dev Sriranganadane, Daiane Laise da Silva, Natália C. Drebes Dörr, Enzo Breviglieri Sichi Mello, Caio Vinicius dos Reis, Rogério Ferreira Lourenço, José Felipe Teixeira da Silva Santos, Anita Salmazo, Brenno Wendler Miranda, Katlin B. Massirer, Rafael M. Couñago, Cristina E. Alvarez‐Martinez   +12 more
wiley   +1 more source

Targeting platelet-tumor cell interactions via thromboxane A₂-prostanoid receptor blockade to reduce metastasis in triple negative breast cancer. [PDF]

Exp Hematol Oncol
Toragall V, Rester AC, Begum S, Shofolawe-Bakare OT, Hulugalla K, Monroe JD, Bentley JP, Gibert Y, Werfel TA.   +8 more
europepmc   +1 more source

The ALS‐associated E425K mutation uncouples DNAJC7 from the Hsp70 chaperone cycle

The FEBS Journal, EarlyView.
DNAJC7 is a J‐domain protein that plays a key role in protein quality control by regulating Hsp70 activity and preventing protein aggregation. We find that the ALS‐associated E425K mutation in DNAJC7 disrupts productive interaction and activation of Hsp70, thereby blocking the transfer and refolding of client proteins such as TDP‐43.
Bar Elmaleh, Ofrah Faust, Rina Rosenzweig   +2 more
wiley   +1 more source

Therapeutic potential of mitotic interaction between the nucleoporin Tpr and aurora kinase A

Cell Cycle, 2015
Akiko Kobayashi, Chieko Hashizume, Takayuki Dowaki, R. Wong   +3 more
semanticscholar   +1 more source

Characterization of error-related potentials during the command of a lower-limb exoskeleton based on deep learning. [PDF]

J Neuroeng Rehabil
Soriano-Segura P, Ortiz M, Polo-Hortigüela C, Iáñez E, Azorín JM.   +4 more
europepmc   +1 more source

AI literacy: A core practice in world language education

Foreign Language Annals, EarlyView.
Abstract The emergence of artificial intelligence (AI) innovations like ChatGPT presents new opportunities and challenges for world languages (WL) education. WL teacher education programs must prepare preservice teachers with AI literacy to help them effectively integrate these technologies into teaching.
Xinyue Lu, Anna Zaitseva, Francis John Troyan   +2 more
wiley   +1 more source

Multimodal feature enhancement via dynamically-aware heterogeneous network for face anti-spoofing. [PDF]

Sci Rep
Yan Y, Shi L, Zhang Y, Chang X.
europepmc   +1 more source

TPR/MET Fusion Protein [PDF]

, 2020
openaire   +1 more source

Exploring a Subpopulation of MASLD Associated With New Onset of CKD Using Supervised Clustering Techniques

Hepatology Research, EarlyView.
The supervised clustering of metabolic dysfunction‐associated steatotic liver disease (MASLD) using a SHapley Additive exPlanations (SHAP)‐converted matrix reveals distinct subpopulations that improved risk stratification for new onset of chronic kidney disease (CKD).
Itaru Hosaka, Marenao Tanaka, Tatsuya Sato, Yukinori Akiyama, Keitaro Nishizawa, Rie Matsumori, Hiroki Aida, Wataru Kawaharata, Kei Nakata, Koki Abe, Toru Suzuki, Hidemichi Kouzu, Naoya Yama, Nagisa Hanawa, Masato Furuhashi   +14 more
wiley   +1 more source

Restoring Sight: The Journey of AIPL1 from Discovery to Therapy. [PDF]

Int J Mol Sci
Galieva A, Karabelsky A, Egorov AD.
europepmc   +1 more source