Results 21 to 30 of about 59,328 (159)

ITK signalling via the Ras/IRF4 pathway regulates the development and function of Tr1 cells

, 2017
Type 1 regulatory T (Tr1) cells differentiate in response to signals engaging the T cell receptor (TCR), express high levels of the immunosuppressive cytokine IL-10, but not Foxp3, and can suppress inflammation and promote immune tolerance.
Koylass, Nicholas, Solouki, Sabrina, Avery August, Weishan Huang, Sabrina Solouki, August, Avery, Nicholas Koylass, Song-Guo Zheng, Huang, Weishan, Zheng, Song-Guo   +9 more
core   +1 more source

Characterization of TR1 levels and activity in RKO cells.

, 2013
Cells were exposed to siRNA directed against TR1 for a total of 96 hrs, and a Sec-deficient C-terminal mutant TR1 was induced for the last 24 hrs. A) Immunoblot analysis of TR1 protein expression following siRNA treatments and induction of the Sec ...
Paul J. Shami (367727), Philip J. Moos (367728), Kornelia Edes (360526), Pamela Cassidy (367726)   +3 more
core   +1 more source

Prostaglandin E2 inhibits Tr1 cell differentiation through suppression of c-Maf.

, 2017
Prostaglandin E2 (PGE2), a major lipid mediator abundant at inflammatory sites, acts as a proinflammatory agent in models of inflammatory/autoimmune diseases by promoting CD4 Th1/Th17 differentiation. Regulatory T cells, including the IL-10 producing Tr1
Weimin Kong, Doina Ganea, Kirsten Mary Hooper   +2 more
core   +1 more source

Key role of macrophages in tolerance induction via T regulatory type 1 (Tr1) cells

, 2020
T regulatory type 1 (Tr1) cells are a class of regulatory T cells (Tregs) participating in peripheral tolerance, hence the rationale behind their testing in clinical trials in different disease settings.
Morsiani C., Mfarrej B., Battaglia M., Gagliani N., Jofra T., Fousteri G.   +5 more
core   +1 more source

Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells

, 2017
Type 1 regulatory T (TR1) cells are Foxp3- interleukin-10 (IL-10)-producing CD4+ T cells with potent immunosuppressive properties, but their requirements for lineage development have remained elusive.
Jason S. Lee, Motoko Koyama, Geoffrey R. Hill, Vuckovic, Slavica, Iain Comerford, Beckett, Kirrilee J., MacDonald, Kelli P., Ping Zhang, Samson, Luke D., Rachel D. Kuns, Iona S. Schuster, Schuster, Iona S., Ullah, Md Ashik, Engwerda, Christian R., Belz, Gabrielle T., Marcela Montes de Oca, Montes de Oca, Marcela, Varelias, Antiopi, Siok-Keen Tey, Shaun R. McColl, Olver, Stuart D., Christian R. Engwerda, Kate H. Gartlan, Thomas, Ranjeny, Kirrilee J. Beckett, Luke D. Samson, de Labastida Rivera, Fabian, Koyama, Motoko, Tey, Siok-Keen, Lee, Jason S., Degli-Esposti, Mariapia A., Ranjeny Thomas, McColl, Shaun R., Axel Kallies, Kuns, Rachel D., Stuart D. Olver, Gabrielle T. Belz, Gartlan, Kate H., Antiopi Varelias, Kelli P. MacDonald, Zhang, Ping, Hill, Geoffrey R., Clouston, Andrew D., Bruce R. Blazar, Kallies, Axel, Andrew D. Clouston, Locke, Kelly R., Blazar, Bruce R., Md Ashik Ullah, Kelly R. Locke, Slavica Vuckovic, Comerford, Iain, Mariapia A. Degli-Esposti, Fabian de Labastida Rivera   +53 more
core   +1 more source

Deep learning based thermal foot segmentation with probability inversion post-processing for automated epidural block assessment

Frontiers in Imaging
IntroductionEpidural analgesia represents the gold standard for labor pain management, yet clinical failure occurs in approximately 9 to 12 percent of cases, adversely affecting maternal well-being and necessitating additional interventions.
Sungjoon Hong, Milan Toma
doaj   +1 more source

Aluminum impairs cellular ultrastructure and bone microarchitecture in newborn rats

Frontiers in Imaging
Modern lifestyle is strongly marked by the presence of aluminum (Al) in practically all human consumer products. Bone tissue is one of the main sites of Al accumulation, and its toxic effects are well known in individuals subjected to chronic exposure ...
Mara Rubia Marques, Anderson Camargo Moreira, Iara Frangiotti Mantovani, Pedro Vale de Azevedo Brito, Isabela Cristina Gomes de Souza Nascimento, Celso Peres Fernandes, Fernanda Cristina Alcantara dos Santos   +6 more
doaj   +1 more source

HCISNet: Higher‐capacity invisible image steganographic network

IET Image Processing, 2021
Information hiding as a crucial method for multimedia security and privacy protection, has received a substantial amount of attention. However, the most existing methods focus on the resistance of steganalysis and the robustness of information, resulting
Yafeng Li, Ju Liu, Xiaoxi Liu, Xuejing Wang, Xuesong Gao, Yuyi Zhang   +5 more
doaj   +1 more source

High-quality deepfakes have a heart!

Frontiers in Imaging
IntroductionDeepfakes have become ubiquitous in our modern society, with both their quantity and quality increasing. The current evolution of image generation techniques makes the detection of manipulated content through visual inspection increasingly ...
Clemens Seibold, Clemens Seibold, Eric L. Wisotzky, Eric L. Wisotzky, Arian Beckmann, Benjamin Kossack, Anna Hilsmann, Peter Eisert, Peter Eisert   +8 more
doaj   +1 more source

Prior‐guided multiscale network for single‐image dehazing

IET Image Processing, 2021
Single‐image dehazing is an important problem because it is a key prerequisite for most high‐level computer vision tasks. Traditional prior‐based methods adopt priors generated from clear images to restrain the atmospheric scattering model and then ...
Nian Wang, Zhigao Cui, Yanzhao Su, Chuan He, Yunwei Lan, Aihua Li   +5 more
doaj   +1 more source