Results 111 to 120 of about 78,864 (334)

Suppression of trabecular meshwork phagocytosis by norepinephrine is associated with nocturnal increase in intraocular pressure in mice

open access: yesCommunications Biology, 2022
Intraocular pressure, which can cause glaucoma, is found to be affected by nocturnal sympathetic noradrenaline, which inhibits phagocytosis in trabecular meshwork cells through β1-aderenergic receptor mediated cAMP-EPAC-SHIP1 activation.
Keisuke Ikegami, Satoru Masubuchi
doaj   +1 more source

High-Resolution, Adaptive Optics Imaging of the Human Trabecular Meshwork In Vivo

open access: yesTranslational Vision Science & Technology, 2019
Purpose To image the human trabecular meshwork (TM) in vivo using adaptive optics gonioscopy (AOG) with approximately 2-μm lateral resolution. Methods An existing Indiana University adaptive optics scanning laser ophthalmoscope was altered by adding a 12-
B. J. King   +4 more
semanticscholar   +1 more source

Transcriptomics Guided Engineering of Exosome‐Encapsulated Bifunctional Nanosheets Targeting the Immune‐PI3K/Akt Axis for Osteoporosis Therapy

open access: yesAdvanced Science, EarlyView.
A multifunctional nanosheet–exosome hybrid system incorporating f‐CA(OH) nanosheets enriched with abundant surface vacancies are developed. These nanosheets fuse with natural exosomes, endowing them with nanozyme‐like catalytic capabilities while retaining their inherent biological functions.
Rongze Tang   +13 more
wiley   +1 more source

TIPARP is involved in the regulation of intraocular pressure

open access: yesCommunications Biology, 2022
TIPARP, an inducible poly-ADP-ribose polymerase, is identified as a novel regulator of intraocular pressure through modulation of extracellular matrix and cell cytoskeleton proteins in trabecular meshwork cells.
Youjia Zhang   +5 more
doaj   +1 more source

Comprehensive bioinformatics analysis of trabecular meshwork gene expression data to unravel the molecular pathogenesis of primary open‐angle glaucoma

open access: yesActa ophthalmologica, 2019
Performing bioinformatics analyses using trabecular meshwork (TM) gene expression data in order to further elucidate the molecular pathogenesis of primary open‐angle glaucoma (POAG), and to identify candidate target genes.
I. Liesenborghs   +7 more
semanticscholar   +1 more source

Evidence for a calcification process in the trabecular meshwork [PDF]

open access: yesExperimental Eye Research, 2009
The human trabecular meshwork (TM) expresses many genes that have been associated with physiological (bone, cartilage, teeth) and pathological (vascular systems, kidney) calcification. In particular, the TM highly expresses the inhibitor of calcification Matrix Gla (MGP) gene, which encodes a vitamin K-dependent protein that requires post-translational
Teresa, Borrás, Núria, Comes
openaire   +2 more sources

Dynamic Regulation of Granular Hydrogels Through Guest‐Host Interactions to Spatiotemporally Guide Cellular Migration

open access: yesAdvanced Science, EarlyView.
A dynamic granular system composed of microgels crosslinked through guest‐host interactions is developed to reversibly alter its stiffness and microporosity in response to chemical stimuli, enabling temporal regulation of cell migration. Suspension bioprinting using this dynamic hydrogel allows for 4D spatiotemporal control over tissue formation ...
Keisuke Nakamura   +4 more
wiley   +1 more source

Optical Coherence Tomography Observation of Gonio Structures during Microhook Ab Interno Trabeculotomy

open access: yesJournal of Ophthalmology, 2017
Introduction. Intraoperative observation of ocular structures using microscope-integrated optical coherence tomography (iOCT) has been adopted recently.
Masaki Tanito
doaj   +1 more source

Iris Morphological Features in Patients with 360° Angle-Closure Neovascular Glaucoma: An Anterior Segment Optical Coherence Tomography Study

open access: yesCase Reports in Ophthalmology, 2018
Purpose: To investigate iris morphological features in 360° angle-closure neovascular glaucoma (NVG) by swept-source anterior segment optical coherence tomography (ASOCT).
Yui Kobayashi   +7 more
doaj   +1 more source

Safety and efficacy of travoprost solution for the treatment of elevated intraocular pressure [PDF]

open access: yes, 2015
Travoprost is a prostaglandin analogue widely used for reducing intraocular pressure (IOP) in patients affected with glaucoma and ocular hypertension. It exerts its ocular hypotensive effect through the prostaglandin FP receptors, located in the ciliary ...
Centofanti, Marco   +5 more
core   +2 more sources

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