Results 181 to 190 of about 26,453 (308)
Phospholipid Interconversion and Transport Are Altered in Glaucoma
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Decreased phosphatidylserine (PS) and increased phosphatidylethanolamine (PE) occur in both trabecular meshwork (TM) cells and aqueous humor due to aberrant phosphatidylserine decarboxylase (PSD) over‐expression, and variation in levels of individual PS or PE species differing by only a few acyl chains occurs due to impaired lipid transport due to ...
Genea Edwards +5 more
wiley +1 more source
TRPV4 regulates intraocular pressure through trabecular meshwork contractility and fibrosis. [PDF]
Channels (Austin)Žavbi J, Redmon SN, Križaj D.
europepmc +1 more source
Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.A tunable methacrylated decellularized bone matrix hydrogel (dECM‐MA) is developed to support 3D culture of human osteoblasts. The hydrogel preserves bone‐specific ECM cues and allows precise control over mechanical properties. This system provides a customizable platform for studying osteogenic differentiation and modeling bone tissue environments for
Minne Dekker +5 more
wiley +1 more source
Quantitative evaluation of trabecular meshwork pigmentation in unilateral Fuchs uveitis syndrome. [PDF]
BMC OphthalmolOzdemir Yalcinsoy K, Uzel MM.
europepmc +1 more source
Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.Nonclinical evaluation of biological responses to implanted medical devices and combination products in animals is required to predict possible outcomes and risks in patients. This paper describes globally accepted pathology “best practices” that 1) effectively address ISO standards and current regulatory guidance for medical device development and 2 ...
Kathleen A. Funk +6 more
wiley +1 more source
TPM2 regulates contractility and biomechanical properties in trabecular meshwork cells. [PDF]
Sci RepShen B +5 more
europepmc +1 more source
Advanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim +5 more
wiley +1 more source
Digoxin Attenuates Ocular Hypertension and Protects Trabecular Meshwork Cells via Ferroptosis Inhibition. [PDF]
Invest Ophthalmol Vis SciZhou X +7 more
europepmc +1 more source
Advanced Healthcare Materials, Volume 15, Issue 1, 9 January 2026.A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer +17 more
wiley +1 more source