Results 211 to 220 of about 16,541 (253)
Some of the next articles are maybe not open access.
Mechanobiology of trabecular meshwork cells
Experimental Eye Research, 2009Trabecular meshwork (TM) cells likely play a key role in regulating outflow facility and hence intraocular pressure. They function in a dynamic environment subjected to variations in mechanical and fluid shear forces. Because the extent of mechanical stress on the trabecular meshwork is dependent on the intraocular pressure, the behavior of TM cells ...
Darrell Wudunn
exaly +3 more sources
Trabecular meshwork and elastin
American Journal of Ophthalmology, 1996Evidence that elastic fibers with elastin exists in the trabecular meshwork (TM) and play an important role in aqueous outflow resistance is presented. The elastic fibers consist of abundant microfibrillar components containing glycoproteins and amorphous components containing elastin.
openaire +2 more sources
Regulation of Trabecular Meshwork Contractility
Ophthalmologica, 2000Ample evidence supports the theory that trabecular meshwork possesses smooth-muscle-like properties. Trabecular meshwork cells express a large number of transporters, channels and receptors, many of which are known to regulate smooth-muscle contractility.
F, Stumpff, M, Wiederholt
openaire +2 more sources
Mechanotransduction Channels of the Trabecular Meshwork
Current Eye Research, 2013To determine whether the trabecular meshwork (TM), like the other organs engaged in filter like activities (such as kidneys), show the expression of known mechanotransduction channels at protein level.Human donor eye globes (n = 20), Donor eye derived TM tissue and primary TM cells were utilized for these studies.
Vu T, Tran +4 more
openaire +2 more sources
The development of human trabecular meshwork
Medical Electron Microscopy, 1994The fetal development of the trabecular meshwork of the human eye was quantitatively studied by light and electron microscopy. From the 20th fetal week onward, the progressive thickening of the trabecular meshwork was achieved mainly by the widening of intertrabecular spaces, whereas the thickness and the number of trabeculae were almost constant ...
T, Sugiura, K, Mizokami, M, Yamamoto
openaire +2 more sources
iPSCs-Based Therapy for Trabecular Meshwork
2023The trabecular meshwork (TM) of the eye serves as an essential tissue in controlling aqueous humor (AH) outflow and intraocular pressure (IOP) homeostasis. However, dysfunctional TM cells and/or decreased TM cellularity is become a critical pathogenic cause for primary open-angle glaucoma (POAG). Consequently, it is particularly valuable to investigate
Wei, Zhu +4 more
openaire +2 more sources
Trabecular Meshwork Phagocytosis in Glaucomatous Eyes
Ophthalmologica, 2010Trabecular meshwork cells are actively phagocytic and may function to keep the drainage pathways free of cellular debris, pigment and other material. A decrease in phagocytic capacity has been proposed in the pathogenesis of glaucoma. This study was performed to compare the phagocytic capability of the human trabecular meshwork in glaucomatous and ...
Y, Matsumoto, D H, Johnson
openaire +2 more sources
Trabecular Meshwork in Normal and Pathological Eyes
Ultrastructural Pathology, 2012The impact of glycosaminoglycans on intraocular pressure in glaucoma patients and in healthy young or aging subjects is explored.Thirty small autoptic samples were harvested from the tissue localized around the iridocorneal angle of the eye, taking care not to cause aesthetic damage.
PESCOSOLIDO, Nicola +3 more
openaire +3 more sources
Glaucoma Associated with Precipitates on the Trabecular Meshwork
Ophthalmology, 1979Precipitates on the trabecular meshwork may be the only sign of ocular inflammation. Fourteen patients who had glaucoma associated with precipitates on the trabecular meshwork and minimal or no other signs of ocular inflammation did not respond to usual antiglaucoma therapy.
M, Roth, R J, Simmons
openaire +2 more sources
Keratan sulphate in the trabecular meshwork and cornea
Current Eye Research, 1997A study was made of the distribution of keratan sulphate in the human anterior chamber.The monoclonal antibody, 5-D-4, was used in immuno-electron microscopy to visualise keratan sulphate distribution in the anterior chamber of 16 normal eyes, 7 Fuchs' dystrophy corneas, and a macular dystrophy cornea.Keratan sulphate was detected in normal human ...
Davis, Y +5 more
openaire +2 more sources