Results 261 to 270 of about 67,374 (288)

Trabecular Meshwork in Normal and Pathological Eyes

Ultrastructural Pathology, 2012
The impact of glycosaminoglycans on intraocular pressure in glaucoma patients and in healthy young or aging subjects is explored.Thirty small autoptic samples were harvested from the tissue localized around the iridocorneal angle of the eye, taking care not to cause aesthetic damage.
PESCOSOLIDO, Nicola, Carlo Cavallotti, Dario Rusciano, NEBBIOSO, Marcella   +3 more
openaire   +4 more sources

Mechanobiology of trabecular meshwork cells

Experimental Eye Research, 2009
Trabecular meshwork (TM) cells likely play a key role in regulating outflow facility and hence intraocular pressure. They function in a dynamic environment subjected to variations in mechanical and fluid shear forces. Because the extent of mechanical stress on the trabecular meshwork is dependent on the intraocular pressure, the behavior of TM cells ...
openaire   +3 more sources

Trabecular meshwork ECM remodeling in glaucoma: could RAS be a target?

Expert opinion on therapeutic targets, 2018
Introduction: Disturbances of extracellular matrix (ECM) homeostasis in trabecular meshwork (TM) cause increased aqueous outflow resistance leading to elevated intraocular pressure (IOP) in glaucomatous eyes.
Puneet Agarwal, R. Agarwal
semanticscholar   +1 more source

Endothelin receptor B in trabecular meshwork

Experimental Eye Research, 2007
Endothelin-1 (ET-1), the most potent vasoconstrictor known to date, seems to be involved in the pathogenesis of primary open angle glaucoma. ET-1 was found in different tissues of the eye and in high concentrations in the aqueous humour. The effects of ET-1 are mediated by two receptors, ET-A receptor (ET-AR) and ET-B receptor (ET-BR), which are both ...
Rüdiger Zorn, Hagen Thieme, Galina Münzer, Rita Rosenthal, Lars Choritz, Lars Choritz, Michael Fromm, Norbert Pfeiffer   +7 more
openaire   +3 more sources

Histopathologic Examination of Trabecular Meshwork Changes After Trabecular Bypass Stent Implantation

Journal of glaucoma, 2018
Purpose: The purpose of this article was to evaluate how human trabecular meshwork (TM) is influenced by the chronic presence of trabecular bypass implants.
Cara E. Capitena Young, D. Ammar, Leonard K. Seibold, M. Pantcheva, J. Soohoo, M. Kahook   +5 more
semanticscholar   +1 more source

Glaucoma Associated with Precipitates on the Trabecular Meshwork

Ophthalmology, 1979
Precipitates on the trabecular meshwork may be the only sign of ocular inflammation. Fourteen patients who had glaucoma associated with precipitates on the trabecular meshwork and minimal or no other signs of ocular inflammation did not respond to usual antiglaucoma therapy.
Michael Roth, Richard J. Simmons
openaire   +3 more sources

Trabecular Meshwork Phagocytosis in Glaucomatous Eyes

Ophthalmologica, 1997
Trabecular meshwork cells are actively phagocytic and may function to keep the drainage pathways free of cellular debris, pigment and other material. A decrease in phagocytic capacity has been proposed in the pathogenesis of glaucoma. This study was performed to compare the phagocytic capability of the human trabecular meshwork in glaucomatous and ...
Yasuhiro Matsumoto, Douglas H. Johnson
openaire   +3 more sources

Proteoglycan expression by human trabecular meshworks

Current Eye Research, 1997
Proteoglycans may serve important roles in trabecular meshwork structure or function. Detailed molecular characterization and identification of specific trabecular proteoglycan core proteins has been limited.Radiolabeled proteoglycans were extracted from cultured human trabecular meshworks and subjected to ion exchange and molecular sieve ...
Nobis Ca, Domreis J, Ted S. Acott, Van Buskirk Em, H Xu, John M. Bradley, Truesdale At, Mary K. Wirtz, Samples   +8 more
openaire   +3 more sources

Morphology of the Trabecular Meshwork

1999
It is well estabilished that in primate eyes most of the resistance to aqueous humor outflow needed for maintenance of a pressure gradient between intraocular pressure of ~ 15 mm Hg and the episcleral venous pressure of ~ 10 mm Hg is located within the trabecular meshwork.
openaire   +2 more sources

Keratan sulphate in the trabecular meshwork and cornea

Current Eye Research, 1997
A study was made of the distribution of keratan sulphate in the human anterior chamber.The monoclonal antibody, 5-D-4, was used in immuno-electron microscopy to visualise keratan sulphate distribution in the anterior chamber of 16 normal eyes, 7 Fuchs' dystrophy corneas, and a macular dystrophy cornea.Keratan sulphate was detected in normal human ...
Davis, Y, Fullwood, N J, Marcyniuk, B, Bonshek, R, Tullo, A, Nieduszynski, I A   +5 more
openaire   +3 more sources