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Characterization, Enrichment, and Computational Modeling of Cross-Linked Actin Networks in Transformed Trabecular Meshwork Cells. [PDF]
Li H +12 more
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Drugs and the trabecular meshwork.
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Regulation of Trabecular Meshwork Contractility
Ophthalmologica, 2000Ample evidence supports the theory that trabecular meshwork possesses smooth-muscle-like properties. Trabecular meshwork cells express a large number of transporters, channels and receptors, many of which are known to regulate smooth-muscle contractility.
F, Stumpff, M, Wiederholt
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iPSCs-Based Therapy for Trabecular Meshwork
2023The trabecular meshwork (TM) of the eye serves as an essential tissue in controlling aqueous humor (AH) outflow and intraocular pressure (IOP) homeostasis. However, dysfunctional TM cells and/or decreased TM cellularity is become a critical pathogenic cause for primary open-angle glaucoma (POAG). Consequently, it is particularly valuable to investigate
Wei, Zhu +4 more
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Trabecular meshwork and elastin
American Journal of Ophthalmology, 1996Evidence that elastic fibers with elastin exists in the trabecular meshwork (TM) and play an important role in aqueous outflow resistance is presented. The elastic fibers consist of abundant microfibrillar components containing glycoproteins and amorphous components containing elastin.
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Endothelin receptor B in trabecular meshwork
Experimental Eye Research, 2007Endothelin-1 (ET-1), the most potent vasoconstrictor known to date, seems to be involved in the pathogenesis of primary open angle glaucoma. ET-1 was found in different tissues of the eye and in high concentrations in the aqueous humour. The effects of ET-1 are mediated by two receptors, ET-A receptor (ET-AR) and ET-B receptor (ET-BR), which are both ...
Rita, Rosenthal +6 more
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Trabecular Meshwork Phagocytosis in Glaucomatous Eyes
Ophthalmologica, 1997Trabecular meshwork cells are actively phagocytic and may function to keep the drainage pathways free of cellular debris, pigment and other material. A decrease in phagocytic capacity has been proposed in the pathogenesis of glaucoma. This study was performed to compare the phagocytic capability of the human trabecular meshwork in glaucomatous and ...
Y, Matsumoto, D H, Johnson
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Proteoglycan expression by human trabecular meshworks
Current Eye Research, 1997Proteoglycans may serve important roles in trabecular meshwork structure or function. Detailed molecular characterization and identification of specific trabecular proteoglycan core proteins has been limited.Radiolabeled proteoglycans were extracted from cultured human trabecular meshworks and subjected to ion exchange and molecular sieve ...
M K, Wirtz +8 more
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