Results 81 to 90 of about 23,257 (267)

Safety and efficacy of travoprost solution for the treatment of elevated intraocular pressure [PDF]

, 2015
Travoprost is a prostaglandin analogue widely used for reducing intraocular pressure (IOP) in patients affected with glaucoma and ocular hypertension. It exerts its ocular hypotensive effect through the prostaglandin FP receptors, located in the ciliary ...
Centofanti, Marco, Floriani, Irene, Katsanos, Andreas, Konstas, Anastasios, Quaranta, Luciano, Riva, Ivano   +5 more
core   +2 more sources

Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering

Medicinal Research Reviews, EarlyView.
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo, Shinwon Kang, Jae Eun Yang, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

NONO‐Related Syndromic X‐Linked Developmental Disability 34: Further Clinical and Molecular Delineation in a Prenatal Cohort

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To characterize the prenatal sonographic features across different trimesters and genomic spectrum of NONO‐related X‐linked intellectual developmental disorder. Method We analyzed two fetuses presenting with corpus callosum agenesis and rare cardiac anomalies using genome sequencing and exome sequencing.
Yilin Zhao, Gang Zou, Mengmeng Shi, Kwok Ming Law, So Ling Lau, Meng Meng, Yuen Ha Ting, Chiu Yee Liona Poon, Zirui Dong, Matthew Hoi Kin Chau, Tak Yeung Leung, Kwong Wai Choy, Xinwen Zhang, Ye Cao   +13 more
wiley   +1 more source

The TGFβ Induced MicroRNAome of the Trabecular Meshwork

Cells
Primary open-angle glaucoma (POAG) is a progressive optic neuropathy with a complex, multifactorial aetiology. Raised intraocular pressure (IOP) is the most important clinically modifiable risk factor for POAG.
Chelsey Doyle, Breedge Callaghan, Anton W. Roodnat, Lee Armstrong, Karen Lester, David A. Simpson, Sarah D. Atkinson, Carl Sheridan, Declan J. McKenna, Colin E. Willoughby   +9 more
doaj   +1 more source

TIPARP is involved in the regulation of intraocular pressure

Communications Biology, 2022
TIPARP, an inducible poly-ADP-ribose polymerase, is identified as a novel regulator of intraocular pressure through modulation of extracellular matrix and cell cytoskeleton proteins in trabecular meshwork cells.
Youjia Zhang, Maomao Song, Yingwen Bi, Yuan Lei, Xinghuai Sun, Yuhong Chen   +5 more
doaj   +1 more source

Anterior chamber flare and central macular thickness after trabeculectomy versus after phacoemulsification

Acta Ophthalmologica, EarlyView.
Abstract Purpose To compare the inflammatory response in the eye after trabeculectomy to after phacoemulsification, focusing on anterior chamber flare (AC flare) and central macular thickness (CMT). Methods Data from 436 participants in two randomized controlled trials were analysed.
Yasmeen Ahmed, Jesper Høiberg Erichsen, Afrouz Ahmadzadeh, Lars Morten Holm, Line Kessel, Daniella Bach‐Holm   +5 more
wiley   +1 more source

Review Of Applied Mathematical Models For Describing The Behaviour Of Aqueous Humor In Eye Structures

International Journal of Applied Mechanics and Engineering, 2015
In the paper, currently used methods for modeling the flow of the aqueous humor through eye structures are presented. Then a computational model based on rheological models of Newtonian and non-Newtonian fluids is proposed. The proposed model may be used
M. Dzierka, P. Jurczak
doaj   +1 more source

Localized and controlled delivery of nitric oxide to the conventional outflow pathway via enzyme biocatalysis: towards therapy for Glaucoma [PDF]

, 2016
Nitric oxide (NO) has been shown to lower intraocular pressure (IOP), however its therapeutic effects on outflow physiology are location- and dose-dependent.
Chandrawati, R, Chang, J, Jumeaux, C, Overby, DR, Reina-Torres, E, Sherwood, JM, Stamer, WD, Stevens, MM, Zelikin, AN   +8 more
core   +1 more source

Variable electrophysiology before and after block of the two delayed rectifier potassium channels in groups of isolated rabbit ventricular cells

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Between‐cell differences in ventricular cardiomyocyte action potential duration (APD) and responses to ion channel block may contribute to pro‐arrhythmic dispersion of myocardial repolarisation. This study quantifies between‐cell physiological and pharmacological variability in the rabbit left ventricle (LV) and uses ...
Rebecca J. Gilchrist, Muhamad Hifzhudin Noor Aziz, Francis L. Burton, Radostin D. Simitev, Rachel C. Myles, Godfrey L. Smith   +5 more
wiley   +1 more source

Biomechanical Analysis of 3D Printed and Thermoformed EVA Custom‐Made Mouthguard: Experimental and Finite Element Analyses

Dental Traumatology, EarlyView.
ABSTRACT Background/Objective 3D printed materials have been evaluated for fabricating mouthguards; however, little is known about their biomechanical performance in preventing dental trauma. This study aimed to compare two 3D printed polymers and three ethylene vinyl acetate (EVA) sheets used for mouthguard fabrication regarding their mechanical ...
Airin Karelys Avendaño Rondon, Izabela Batista Cordeiro, Maribí Isomar Terán Lozada, Gustavo Mendonça, Priscilla Barbosa Ferreira Soares, Paulo Sergio Borella, Carlos José Soares   +6 more
wiley   +1 more source