Results 121 to 130 of about 15,334 (193)

Low-dose radiation by radiopharmaceutical therapy enhances GD2 <i>TRAC</i>-CAR T cell efficacy in localized neuroblastoma. [PDF]

Sci Adv
Sodji QH, Shea A, Cappabianca D, Forsberg MH, Eickhoff JC, Idrissou MB, Ollendorff AS, Kwon O, Ong IM, Hernandez R, Weichert J, Bednarz BP, Saha K, Sondel PM, Capitini CM, Morris ZS.   +15 more
europepmc   +1 more source

Preventing secondary primary malignancies (SPMs) in CAR-T cell therapy through site-specific transgene integration into genomic safe harbors (GSHs). [PDF]

J Transl Med
Safarzadeh Kozani P, Safarzadeh Kozani P.   +1 more
europepmc   +1 more source

Cohort profile: Design and methods for Project HERCULES (Healthcare Exemplar for Recovery from COVID 19 Using Linear Examination Systems): Multi-disciplinary implementation and evaluation of an asynchronous review clinic in NHS eye-care services. [PDF]

PLoS One
Muhundhakumar D, Clarke CS, Mills G, Ramsay AIG, Sailer K, Scully P, Wilson D, Fu DJ, Ndwandwe S, Pachilova R, Symons A, Napier S, Adesanya J, Gazzard G, Hamilton R, Wilson J, Webster P, Khaw PT, Sivaprasad S, Jayaram H, Foster PJ, HERCULES Consortium.   +21 more
europepmc   +1 more source

c-JUN enhances CRISPR knockin anti-B7-H3 CAR T cell function in small cell lung cancer and thoracic SMARCA4-deficient undifferentiated tumors. [PDF]

Cell Rep Med
Balke-Want H, Keerthi V, Del Carmen Arenas M, Chen Y, Malipatlolla M, Klysz DD, Xu P, Ho K, Asano K, Stahl D, Huang J, Retherford A, Patel S, Fowler C, Maas L, Gkitsas-Long N, Jiang Q, Liu X, Ullrich R, George J, Heitzeneder S, Tunuguntla R, Sage J, Sotillo E, Mackall CL, Feldman SA.   +25 more
europepmc   +1 more source

High-efficiency homology-directed insertion into the genome using the engineered homing endonuclease ARCUS. [PDF]

Nucleic Acids Res
Resly LC, Tubbs AL, Vogel AJ, Hux JA, MacDonald IA, Harris J, Mischler A, Tomberlin GH, Evans KS, Thompson R, Sunman J, Lape J, Smith JJ, Martin AJ.   +13 more
europepmc   +1 more source

Multiplex engineering and multifunction T cells for precise and effective immunotherapies. [PDF]

Front Immunol
Jafarzadeh L, Smaani A, Delisle JS.
europepmc   +1 more source

CRISPR tools for T cells: targeting the genome, epigenome, and transcriptome. [PDF]

Trends Cancer
Wachsmann TLA, Qi LS.
europepmc   +1 more source

Orthogonal CRISPR systems for targeted integration and multiplex base editing enable nonviral engineering of allogeneic CAR-T cells. [PDF]

Mol Ther
Mikkelsen NS, Ravendran S, Broksø AD, Skjelbostad SF, Pedersen MG, Fang H, Terkelsen T, Thomsen MK, Bak RO.   +8 more
europepmc   +1 more source

Harnessing the potential of gene editing technology for CAR-T cell therapy of solid tumors. [PDF]

Inflamm Regen
Khodabandehloo E, Rayati M, Ahmadi E, Naghdibadi M, Moradi V, Ahmadbeigi N.   +5 more
europepmc   +1 more source

The companion dog as a translational model for Alzheimer's disease: Development of a longitudinal research platform and post mortem protocols. [PDF]

Alzheimers Dement
McGrath S, Hull E, Dunbar MD, Prescott J, Keyser AJ, MacLean E, Darvas M, Latimer C, Moreno J, MacCoss MJ, Kauffman M, Litwin P, Castelhano M, Kaeberlein M, Keene CD, Dog Aging Project Consortium.   +15 more
europepmc   +1 more source