Results 31 to 40 of about 3,014,545 (296)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
A rapid, accurate, and high performance method of high resolution sector field inductively coupled plasma mass spectrometry (HR-ICP-MS) combined with a small-size sample (0.1 mL) preparation was established.
Xiaobing Liu +6 more
doaj +1 more source
Resurgence is a term which implies that a stream courses beneath the surface before it issues from the ground. This concept seems to be linked to the notion of disappearance by a relation of temporal causality.
Maylis Rospide
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Environmental impact assessments have a primary goal of balancing anthropogenic development with environmental protection. While critique methodologies for standard impact assessments are well-established, existing frameworks often fall short in ...
Trace Laskey
doaj +1 more source
This article investigates the concept of ghost places as a tool for understanding the post-conflict situation in Lebanon. The reflection carried out relies on two field studies: Beirut’s nightscape and memory sites in Southern Lebanon. These spaces have
Marie Bonte, Zara Fournier
doaj +1 more source
Drug Policy and the HIV Pandemic in Russia and Ukraine [PDF]
Over the past three years Russia and Ukraine have experienced one of the fastest growing HIV pandemics in Europe. In contrast to other parts of the world, the main driver behind the rate of infection is injecting drug use. Recent government policies have
Klein, Axel +2 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Multi-Trace Superpotentials vs. Matrix Models [PDF]
We consider N = 1 supersymmetric U(N) field theories in four dimensions with adjoint chiral matter and a multi-trace tree-level superpotential. We show that the computation of the effective action as a function of the glueball superfield localizes to ...
Balasubramanian, Vijay +6 more
core +4 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

