Results 61 to 70 of about 3,014,545 (296)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Further generalized refinement of Young’s inequalities for τ -mesurable operators
Moroccan Journal of Pure and Applied Analysis, 2021 In this paper, we prove that if a, b > 0 and 0 ≤ v ≤ 1.
Ighachane Mohamed Amine +1 more
doaj +1 more source
, 1992 We are proud of our unparalleled collection of specialized encyclopedias. We are now trying to trace the whereabouts of the following lost volumes.
McManus, Christopher
core +1 more source
Microlocal Lefschetz classes of graph trace kernels
, 2016 In this paper, we define the notion of graph trace kernels as a generalization of trace kernels. We associate a microlocal Lefschetz class with a graph trace kernel and prove that this class is functorial with respect to the composition of kernels.
Ike, Yuichi
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
L’apostrophe de l’événement: Romano à la lumière de Badiou et Marion
Journal of French and Francophone Philosophy, 2013 Les pensées contemporaines de l’événement, tout comme la langue de tous, déterminent l’événement comme étant une exception sur l’ordre normal du monde. À la différence des faits, les événements ont un caractère exceptionnel qui provient pour l’essentiel ...
Stéphane Vinolo
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Treatment of lack of information in process mining
Revista Facultad de Ingeniería Universidad de Antioquia, 2014 Process mining is a research discipline including discovery, monitoring and improvement of real processes by extracting knowledge from event logs readily available in today's information systems. Most process mining algorithms assume that the traces are
Raykenler Yzquierdo-Herrera +2 more
doaj +1 more source
Some Universal Properties for Restricted Trace Gaussian Orthogonal, Unitary and Symplectic Ensembles
, 2010 Consider fixed and bounded trace Gaussian orthogonal, unitary and symplectic ensembles, closely related to Gaussian ensembles without any constraint. For three restricted trace Gaussian ensembles, we prove universal limits of correlation functions at ...
A. Soshnikov +29 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source