Results 91 to 100 of about 1,844,938 (269)

Scalar Gravitational Waves in the Effective Theory of Gravity

, 2017
As a low energy effective field theory, classical General Relativity receives an infrared relevant modification from the conformal trace anomaly of the energy-momentum tensor of massless, or nearly massless, quantum fields.
Mottola, Emil
core   +1 more source

Effect of Trace Scandium Addition on Al-6mg Alloy

Journal of Mechanical Engineering, 1970
Ageing behaviour of Al-6Mg alloy doped with trace amount of scandium was investigated. Cold rolled and as cast samples were aged isochronally for 60 minutes at different temperature up to 500°C. Some samples were aged isothermally at 300°C for different periods ranging from 30 to 240 minutes.
openaire   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Beyond graph energy: norms of graphs and matrices

, 2016
In 1978 Gutman introduced the energy of a graph as the sum of the absolute values of graph eigenvalues, and ever since then graph energy has been intensively studied.
Nikiforov, Vladimir
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Trace element delivery for biogas production enhanced by alternative energy crops: results from two-year field trials

Energy, Sustainability and Society, 2018
Background Energy crop production for biogas still relies mainly on maize, but the co-digestion of alternative energy crops (legumes, amaranth, ryegrass, flower mixtures) with maize can have several advantages. First, a greater biodiversity in the fields;
Wiebke Fahlbusch, Katharina Hey, Benedikt Sauer, Hans Ruppert   +3 more
doaj   +1 more source

Molecular Tracers of the Central 12 pc of the Galactic Center

, 2000
We have used the BIMA array to image the Galactic Center with a 19-pointing mosaic in HCN(1-0), HCO+(1-0), and H 42-alpha emission with 5 km/s velocity resolution and 13'' x 4'' angular resolution.
Alison L. Coil, Andrew. I. Harris, Bieging J., Ekers R. D., Genzel R., Goss W. M., Gusten R., Gusten R., Marshall J., Melvyn C. H. Wright, Mezger P. G., Nejad L. A. M., Paul T. P. Ho, Robeson S. McGary, Serabyn E., Steer D. G., Zylka R.   +16 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source