Results 61 to 70 of about 4,900,225 (242)

The role of zinc homeostasis in major depressive disorder: heterogeneous pathological mechanisms and therapeutic implications

Annals of Medicine
Background Major depressive disorder (MDD) involves multifaceted pathologies including neurotransmission, neuroplasticity, inflammation, and hypothalamic-pituitary-adrenal (HPA) axis dysfunction.
Yuping Li, Yucui Lu, Xianmei Lin, Lichun Zhao   +3 more
doaj   +1 more source

A large-scale polygenic risk score analysis identified candidate proteins associated with anxiety, depression and neuroticism

Molecular Brain, 2022
Psychiatric disorders and neuroticism are closely associated with central nervous system, whose proper functioning depends on efficient protein renewal. This study aims to systematically analyze the association between anxiety / depression / neuroticism ...
Bolun Cheng, Xuena Yang, Shiqiang Cheng, Chun’e Li, Huijie Zhang, Li Liu, Peilin Meng, Yumeng Jia, Yan Wen, Feng Zhang   +9 more
doaj   +1 more source

Abnormal expression of TSG-6 disturbs extracellular matrix homeostasis in chondrocytes from endemic osteoarthritis

Frontiers in Genetics, 2022
Background and aims: Kashin-Beck disease (KBD) is a unique endemic osteochondropathy with unclear pathogenesis in China. T-2 toxin exposure has been identified as a significant risk factor of KBD.
Yujie Ning, Pan Zhang, Feiyu Zhang, Sijie Chen, Yanli Liu, Feihong Chen, Yifan Wu, Shujin Li, Chaowei Wang, Yi Gong, Minhan Hu, Ruitian Huang, Hongmou Zhao, Xiong Guo, Xiong Guo, Xi Wang, Lei Yang   +16 more
doaj   +1 more source

The influence of the quantity and quality of sediment organic matter on the potential mobility and toxicity of trace elements in bottom sediment

Environmental Geochemistry and Health, 2019
Knowledge on the fraction of trace elements in the bottom sediments is a key to understand their mobility and ecotoxicological impact. The purpose of this study was to assess the influence of the content of organic matter fractions on the mobility and ...
A. Baran, M. Mierzwa-Hersztek, K. Gondek, M. Tarnawski, Magdalena Szara, Olga Gorczyca, Tomasz Koniarz   +6 more
semanticscholar   +1 more source

Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort

Molecular Brain, 2021
Objective To evaluate the genetic effects of sex hormone traits on the development of mental traits in middle-aged adults. Methods The SNPs associated with sex hormone traits were derived from a two-stage genome-wide association study (GWAS).
Xiao Liang, ShiQiang Cheng, Jing Ye, XiaoMeng Chu, Yan Wen, Li Liu, Xin Qi, YuMeng Jia, Feng Zhang   +8 more
doaj   +1 more source

Trace Element Estimation – Methods & Clinical Context [PDF]

, 2005
Understanding the effects of trace metals on human health is as complex as it is fascinating. As mentioned earlier, the high concentrations may prove toxic, as also, depletion in the concentration of the essential trace elements may cause various ...
Rao Nanjunda, Dr. Ananth
core   +1 more source

Dynamic and Stable Core Microbiota Assist Plants in Enriching Selenium and Reducing Cadmium Absorption

Advanced Science
Rhizosphere microbiome is crucial for regulating rhizosphere complex nutrient dynamics. However, mechanisms by which plants regulate rhizosphere microbes to manage nutrient availability under coexisting beneficial and harmful elements remain unclear ...
Zheng Lei, Hua Zhang, Wenju Liu, Jiandong Sheng, Huan Zhang, Yin Wang, Yanni Tang, Huaxing Wang, Cuicui Ding, Wanqi Qiao, Yonghui Zhu, Guoyin Yang, Yihan Zhang, Zhuoyi Liu, Nanyu Zhou, Chengxiao Hu, Xiaohu Zhao   +16 more
doaj   +1 more source

Genome-wide DNA methylation profile analysis identifies differentially methylated loci associated with ankylosis spondylitis

Arthritis Research & Therapy, 2017
Background Ankylosing spondylitis (AS) is a chronic rheumatic and autoimmune disease. Little is known about the potential role of DNA methylation in the pathogenesis of AS. This study was undertaken to explore the potential role of DNA methylation in the
Jiangcan Hao, Yang Liu, Jiawen Xu, Wenyu Wang, Yan Wen, Awen He, Qianrui Fan, Xiong Guo, Feng Zhang   +8 more
doaj   +1 more source

Dual Role of Metallic Trace Elements in Stress Biology—From Negative to Beneficial Impact on Plants

International Journal of Molecular Sciences, 2019
Heavy metals are an interesting group of trace elements (TEs). Some of them are minutely required for normal plant growth and development, while others have unknown biological actions.
E. Muszyńska, M. Labudda
semanticscholar   +1 more source

Trace elements in rye - comparison of organic and conventional cultivation [PDF]

, 2003
The trials included comparison of four rye cultivars grown in organic and conventional farming systems at three locations during 1999 ...
Eurola, Merja, Hietaniemi, Veli, Laine, Antti, Niskanen, Markku, Vuorinen, Martti   +4 more
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