Results 41 to 50 of about 3,436,813 (308)

Trace elements in stream bed sediments from agricultural catchments (Gascogne region, S-W France): Where do they come from? [PDF]

open access: yes, 2009
The Gascogne region (SW of France) is cultivated for more than 75% of the area. 83 samples of stream bed sediments were collected in three main Gascogne river basins (Gers, Save and Touch, left tributaries of the Garonne river) to evaluate the impact of ...
Probst, Jean-Luc   +3 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Impact of soil-type, soil-pH, and soil-metal (loids) on grain-As and Cd accumulation in Malawian rice grown in three regions of Malawi

open access: yesEnvironmental Advances, 2022
Impact of soil type, soil-metal(loids) and soil-pH of rice paddies on grain-arsenic (As) and cadmium (Cd) accumulation in Malawian rice was investigated to explore the extent to which Malawi's geographical location, soil types, soil-metal(loids) and soil-
Angstone Thembachako Mlangeni   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Assessing particle count in electron microscopy measurements of nanomaterials to support regulatory guidance

open access: yesScientific Reports
In the European Union, nanomaterials are regulated through different pieces of sectoral legislation. This legislation often requires risk assessments and thus reliable characterization data, for which regulatory guidance generally recommend electron ...
Charlotte Wouters   +3 more
doaj   +1 more source

A large-scale polygenic risk score analysis identified candidate proteins associated with anxiety, depression and neuroticism

open access: yesMolecular Brain, 2022
Psychiatric disorders and neuroticism are closely associated with central nervous system, whose proper functioning depends on efficient protein renewal. This study aims to systematically analyze the association between anxiety / depression / neuroticism ...
Bolun Cheng   +9 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Trace elements in rock salt and their bioavailability estimated from solubility in acid

open access: yes, 2006
In this study, 18 partly commercially available samples of rock salt from Austria, Germany, Pakistan, Poland, Switzerland, and Ukraine were investigated with respect to their content of trace elements using instrumental neutron activation analysis ...
Steinhauser, Georg   +4 more
core   +4 more sources

Mendelian randomization study of the relationship between blood and urine biomarkers and schizophrenia in the UK Biobank cohort

open access: yesCommunications Medicine
Background The identification of suitable biomarkers is of crucial clinical importance for the early diagnosis of treatment-resistant schizophrenia (TRS).
Bolun Cheng   +11 more
doaj   +1 more source

The role of zinc homeostasis in major depressive disorder: heterogeneous pathological mechanisms and therapeutic implications

open access: yesAnnals of Medicine
Background Major depressive disorder (MDD) involves multifaceted pathologies including neurotransmission, neuroplasticity, inflammation, and hypothalamic-pituitary-adrenal (HPA) axis dysfunction.
Yuping Li   +3 more
doaj   +1 more source

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