Results 21 to 30 of about 193,784 (268)

Trace Elements and Nitrification

open access: yesNature, 1948
THE exact requirements of the nitrifying bacteria for inorganic nutrients are not yet known, though all workers on this group since Winogradsky1 have assumed that they require iron, and many workers have added traces of other metals to their media2, or used tap-water as a diluent, because of the possible trace elements it contains3.
Lees, H., Meiklejohn, J.
openaire   +2 more sources

An integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder

open access: yesInternational Journal of Bipolar Disorders, 2020
Background Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown. Methods We conducted an integrative analysis of genome-wide association study (GWAS) and regulatory SNP (rSNP) annotation datasets ...
Xin Qi   +10 more
doaj   +1 more source

CRISP-R/Cas9 Mediated Deletion of Copper Transport Genes CTR1 and DMT1 in NSCLC Cell Line H1299. Biological and Pharmacological Consequences

open access: yesCells, 2019
Copper, the highly toxic micronutrient, plays two essential roles: it is a catalytic and structural cofactor for Cu-dependent enzymes, and it acts as a secondary messenger.
Ekaterina Y. Ilyechova   +5 more
doaj   +1 more source

Evaluating the effect of birth weight on brain volumes and depression: An observational and genetic study using UK Biobank cohort

open access: yesEuropean Psychiatry, 2020
Background.Birth weight influences not only brain development, but also mental health outcomes, including depression, but the underlying mechanism is unclear.Methods.The phenotypic data of 12,872–91,009 participants (59.18–63.38% women) from UK Biobank ...
Jing Ye   +17 more
doaj   +1 more source

Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China

open access: yesArthritis Research & Therapy, 2022
Background Osteoarthritis (OA) and Kashin-Beck disease (KBD) both are two severe osteochondral disorders. In this study, we aimed to compare the gut microbiota structure between OA and KBD patients.
Yujie Ning   +15 more
doaj   +1 more source

Longitudinal relationship between body fat percentage and risk of type 2 diabetes in Chinese adults: Evidence from the China Health and Nutrition Survey

open access: yesFrontiers in Public Health, 2022
ObjectiveBody fat percentage (BF%) might be an alternative index of obesity which is the major risk factor for developing type 2 diabetes (T2D). We aim to longitudinally evaluated the relationship between BF% and risk of T2D.MethodsA sample of 5,595 ...
Siting Zhang   +16 more
doaj   +1 more source

Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis

open access: yesArthritis Research & Therapy, 2021
Objective To identify rheumatoid arthritis (RA)-associated susceptibility genes and pathways through integrating genome-wide association study (GWAS) and gene expression profile data. Methods A transcriptome-wide association study (TWAS) was conducted by
Cuiyan Wu   +11 more
doaj   +1 more source

Trace elements in dialysis [PDF]

open access: yesPediatric Nephrology, 2013
In end-stage chronic kidney disease (CKD), pediatric nephrologists must consider the homeostasis of the multiple water-soluble ions that are influenced by renal replacement therapy (RRT). While certain ions such as potassium and calcium are closely monitored, little is known about the handling of trace elements in pediatric dialysis.
Filler, Guido, Felder, Sarah
openaire   +4 more sources

Comparison of microRNA expression profiles of Kashin-Beck disease, osteoarthritis and rheumatoid arthritis

open access: yesScientific Reports, 2017
Kashin-Beck disease (KBD) is a chronic osteochondropathy with unclear pathogeny. In this study, we compared the microRNA expression profiles of 16 KBD patients, 16 osteoarthritis (OA) patients and 16 rheumatoid arthritis (RA) patients and 16 healthy ...
Wenhong Wu   +6 more
doaj   +1 more source

Identifying discriminative features for diagnosis of Kashin-Beck disease among adolescents

open access: yesBMC Musculoskeletal Disorders, 2021
Introduction Diagnosing Kashin-Beck disease (KBD) involves damages to multiple joints and carries variable clinical symptoms, posing great challenge to the diagnosis of KBD for clinical practitioners.
Yanan Zhang   +11 more
doaj   +1 more source

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