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Trace Elements and Nitrification
THE exact requirements of the nitrifying bacteria for inorganic nutrients are not yet known, though all workers on this group since Winogradsky1 have assumed that they require iron, and many workers have added traces of other metals to their media2, or used tap-water as a diluent, because of the possible trace elements it contains3.
Lees, H., Meiklejohn, J.
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Background Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown. Methods We conducted an integrative analysis of genome-wide association study (GWAS) and regulatory SNP (rSNP) annotation datasets ...
Xin Qi +10 more
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Copper, the highly toxic micronutrient, plays two essential roles: it is a catalytic and structural cofactor for Cu-dependent enzymes, and it acts as a secondary messenger.
Ekaterina Y. Ilyechova +5 more
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Background.Birth weight influences not only brain development, but also mental health outcomes, including depression, but the underlying mechanism is unclear.Methods.The phenotypic data of 12,872–91,009 participants (59.18–63.38% women) from UK Biobank ...
Jing Ye +17 more
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Background Osteoarthritis (OA) and Kashin-Beck disease (KBD) both are two severe osteochondral disorders. In this study, we aimed to compare the gut microbiota structure between OA and KBD patients.
Yujie Ning +15 more
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ObjectiveBody fat percentage (BF%) might be an alternative index of obesity which is the major risk factor for developing type 2 diabetes (T2D). We aim to longitudinally evaluated the relationship between BF% and risk of T2D.MethodsA sample of 5,595 ...
Siting Zhang +16 more
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Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis
Objective To identify rheumatoid arthritis (RA)-associated susceptibility genes and pathways through integrating genome-wide association study (GWAS) and gene expression profile data. Methods A transcriptome-wide association study (TWAS) was conducted by
Cuiyan Wu +11 more
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Trace elements in dialysis [PDF]
In end-stage chronic kidney disease (CKD), pediatric nephrologists must consider the homeostasis of the multiple water-soluble ions that are influenced by renal replacement therapy (RRT). While certain ions such as potassium and calcium are closely monitored, little is known about the handling of trace elements in pediatric dialysis.
Filler, Guido, Felder, Sarah
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Kashin-Beck disease (KBD) is a chronic osteochondropathy with unclear pathogeny. In this study, we compared the microRNA expression profiles of 16 KBD patients, 16 osteoarthritis (OA) patients and 16 rheumatoid arthritis (RA) patients and 16 healthy ...
Wenhong Wu +6 more
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Identifying discriminative features for diagnosis of Kashin-Beck disease among adolescents
Introduction Diagnosing Kashin-Beck disease (KBD) involves damages to multiple joints and carries variable clinical symptoms, posing great challenge to the diagnosis of KBD for clinical practitioners.
Yanan Zhang +11 more
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