Results 21 to 30 of about 3,436,813 (308)

Assessing the effect of interaction between gut microbiome and inflammatory bowel disease on the risks of depression

Brain, Behavior, & Immunity - Health, 2022
Background: Gut microbiome and inflammatory bowel disease (IBD) are implicated in the development of depression, but the effect of their interactions on the risk of depression remains unclear.
Xiaoyue Qin, Chuyu Pan, Qingqing Cai, Yijing Zhao, Dan He, Wenming Wei, Na Zhang, Sirong Shi, Xiaoge Chu, Feng Zhang   +9 more
doaj   +1 more source

Trace Elements and Nitrification

Nature, 1948
THE exact requirements of the nitrifying bacteria for inorganic nutrients are not yet known, though all workers on this group since Winogradsky1 have assumed that they require iron, and many workers have added traces of other metals to their media2, or used tap-water as a diluent, because of the possible trace elements it contains3.
Lees, H., Meiklejohn, J.
openaire   +2 more sources

CRISP-R/Cas9 Mediated Deletion of Copper Transport Genes CTR1 and DMT1 in NSCLC Cell Line H1299. Biological and Pharmacological Consequences

Cells, 2019
Copper, the highly toxic micronutrient, plays two essential roles: it is a catalytic and structural cofactor for Cu-dependent enzymes, and it acts as a secondary messenger.
Ekaterina Y. Ilyechova, Elisa Bonaldi, Iurii A. Orlov, Ekaterina A. Skomorokhova, Ludmila V. Puchkova, Massimo Broggini   +5 more
doaj   +1 more source

An integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder

International Journal of Bipolar Disorders, 2020
Background Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown. Methods We conducted an integrative analysis of genome-wide association study (GWAS) and regulatory SNP (rSNP) annotation datasets ...
Xin Qi, Yan Wen, Ping Li, Chujun Liang, Bolun Cheng, Mei Ma, Shiqiang Cheng, Lu Zhang, Li Liu, Om Prakash Kafle, Feng Zhang   +10 more
doaj   +1 more source

Comparative analysis of the gut microbiota composition between knee osteoarthritis and Kashin-Beck disease in Northwest China

Arthritis Research & Therapy, 2022
Background Osteoarthritis (OA) and Kashin-Beck disease (KBD) both are two severe osteochondral disorders. In this study, we aimed to compare the gut microbiota structure between OA and KBD patients.
Yujie Ning, Minhan Hu, Yi Gong, Ruitian Huang, Ke Xu, Sijie Chen, Feiyu Zhang, Yanli Liu, Feihong Chen, Yanhai Chang, Guanghui Zhao, Cheng Li, Rong Zhou, Mikko J. Lammi, Xiong Guo, Xi Wang   +15 more
doaj   +1 more source

Longitudinal relationship between body fat percentage and risk of type 2 diabetes in Chinese adults: Evidence from the China Health and Nutrition Survey

Frontiers in Public Health, 2022
ObjectiveBody fat percentage (BF%) might be an alternative index of obesity which is the major risk factor for developing type 2 diabetes (T2D). We aim to longitudinally evaluated the relationship between BF% and risk of T2D.MethodsA sample of 5,595 ...
Siting Zhang, Hongru Jiang, Hongru Jiang, Liusen Wang, Liusen Wang, Xiaofang Jia, Xiaofang Jia, Jiguo Zhang, Jiguo Zhang, Huijun Wang, Huijun Wang, Bing Zhang, Bing Zhang, Zhihong Wang, Zhihong Wang, Gangqiang Ding, Gangqiang Ding   +16 more
doaj   +1 more source

Evaluating the effect of birth weight on brain volumes and depression: An observational and genetic study using UK Biobank cohort

European Psychiatry, 2020
Background.Birth weight influences not only brain development, but also mental health outcomes, including depression, but the underlying mechanism is unclear.Methods.The phenotypic data of 12,872–91,009 participants (59.18–63.38% women) from UK Biobank ...
Jing Ye, Cuiyan Wu, Xiaomeng Chu, Yan Wen, Ping Li, Bolun Cheng, Shiqiang Cheng, Li Liu, Lu Zhang, Mei Ma, Xin Qi, Chujun Liang, Om Prakash Kafle, Yumeng Jia, Sen Wang, Xi Wang, Yujie Ning, Feng Zhang   +17 more
doaj   +1 more source

Transcriptome-wide association study identifies susceptibility genes for rheumatoid arthritis

Arthritis Research & Therapy, 2021
Objective To identify rheumatoid arthritis (RA)-associated susceptibility genes and pathways through integrating genome-wide association study (GWAS) and gene expression profile data. Methods A transcriptome-wide association study (TWAS) was conducted by
Cuiyan Wu, Sijian Tan, Li Liu, Shiqiang Cheng, Peilin Li, Wenyu Li, Huan Liu, Feng’e Zhang, Sen Wang, Yujie Ning, Yan Wen, Feng Zhang   +11 more
doaj   +1 more source

Pollution and risks of trace elements in the soil environment

, 2022
Trace elements may be either essential or toxic to organisms. The most common trace elements in soils are Cd, As, Cr, Hg, Pb, Ni, Zn, and Cu. Pollution of trace elements in soils may be natural or anthropogenic, with the latter including agricultural and
Wang, P., Zhao, F-J., McGrath, S. P.
core   +1 more source

Comparison of microRNA expression profiles of Kashin-Beck disease, osteoarthritis and rheumatoid arthritis

Scientific Reports, 2017
Kashin-Beck disease (KBD) is a chronic osteochondropathy with unclear pathogeny. In this study, we compared the microRNA expression profiles of 16 KBD patients, 16 osteoarthritis (OA) patients and 16 rheumatoid arthritis (RA) patients and 16 healthy ...
Wenhong Wu, Awen He, Yan Wen, Xiao Xiao, Jingcan Hao, Feng Zhang, Xiong Guo   +6 more
doaj   +1 more source