Results 1 to 10 of about 1,061 (155)

Effects of selenium and iodine on Kashin-Beck disease: an updated review [PDF]

Frontiers in Nutrition
Kashin-Beck disease (KBD) is an endochondral osteogenesis disorder characterised by epiphysis damage and secondary deformable arthropathy induced by multiple external factors, among which selenium (Se) and iodine deficiency are important influencing ...
Lin Liu, Pan Luo, Pengfei Wen, Peng Xu
doaj   +4 more sources

Disease and Economic Burden of Kashin-Beck Disease - China, 2021‎. [PDF]

China CDC Wkly
Kashin-Beck disease (KBD) is a chronic and degenerative osteoarthropathy characterized by cartilage degeneration. It is an endemic disease that is highly prevalent among the Chinese population and poses a significant health risk.This is the first national report on the economic burden of KBD in China.
Cui S, Que W, Jiao Z, Deng Q, Zhang X, Cao Y, Liu N, Li A, Sowanou A, Li Z, Wang T, Li Y, Yu J, Pei J.   +13 more
europepmc   +4 more sources

The molecular mechanism study of COMP involved in the articular cartilage damage of Kashin-Beck disease [PDF]

Bone & Joint Research, 2020
Aims: Kashin-Beck disease (KBD) is a kind of chronic osteochondropathy, thought to be caused by environmental risk factors such as T-2 toxin. However, the exact aetiology of KBD remains unclear.
Mei Ma, Xiao Liang, Xi Wang, Lu Zhang, Shiqiang Cheng, Xiong Guo, Feng Zhang, Yan Wen   +7 more
doaj   +4 more sources

A study on atypical Kashin–Beck disease: an endemic ankle arthritis [PDF]

Journal of Orthopaedic Surgery and Research, 2023
Background To study the epidemiological characteristics of atypical Kashin–Beck disease cases without characteristic hand lesions such as interphalangeal joint enlargement and brachydactyly and the characteristics of ankle joint lesions.
Fang Qi, Si-Lu Cui, Bing Zhang, Hao-Nan Li, Jun Yu   +4 more
doaj   +2 more sources

Differential expression of cyclins CCNB1 and CCNG1 is involved in the chondrocyte damage of kashin-beck disease [PDF]

Frontiers in Genetics, 2022
The purpose of this study was clarify the relationship between the differential expression of cyclins CCNB1 and CCNG1 and chondrocyte damage in Kashin-Beck disease. Systematic review and high-throughput sequencing of chondrocytes derived from Kashin-Beck
Kaidiriye Setiwalidi, Jialei Fu, He Hei, Shaniya Nuer, Feiyu Zhang, Sijie Chen, Yanli Liu, Feihong Chen, Shujin Li, Chaowei Wang, Yifan Wu, Yi Gong, Minhan Hu, Ruitian Huang, Junyi Liu, Tianxiao Zhang, Yujie Ning, Hongmou Zhao, Xiong Guo, Xiong Guo, Xi Wang   +20 more
doaj   +2 more sources

Untargeted Metabolomics Approach Correlated Enniatin B Mycotoxin Presence in Cereals with Kashin–Beck Disease Endemic Regions of China [PDF]

Toxins, 2023
Kashin–Beck disease (KBD) is a multifactorial endemic disease that only occurs in specific Asian areas. Mycotoxin contamination, especially from the Fusarium spp., has been considered as one of the environmental risk factors that could provoke ...
Danlei Sun, Camille Chasseur, Françoise Mathieu, Jessica Lechanteur, Pierre Van Antwerpen, Joanne Rasschaert, Véronique Fontaine, Cédric Delporte   +7 more
doaj   +2 more sources

Detection of selenoprotein transcriptome in chondrocytes of patients with Kashin–Beck disease [PDF]

Frontiers in Cell and Developmental Biology, 2023
Background: Kashin–Beck disease (KBD) is a deformed osteochondral disease with a chronic progression that is restrictively distributed in eastern Siberia, North Korea, and some areas of China, and selenium deficiency has been identified as an important ...
Yi Gong, Yifan Wu, Yanli Liu, Sijie Chen, Feiyu Zhang, Feihong Chen, Chaowei Wang, Shujin Li, Minhan Hu, Ruitian Huang, Ke Xu, Xi Wang, Lei Yang, Yujie Ning, Cheng Li, Rong Zhou, Xiong Guo, Xiong Guo   +17 more
doaj   +2 more sources

Combined Proximal Tibial Osteotomy for Adult Kashin–Beck Disease with Severe Varus Knee Osteoarthritis: Case Report and Literature Review [PDF]

Orthopaedic Surgery, 2022
Background Kashin–Beck disease (KBD) is an endemic, chronic osteoarthropathy that seriously affects joint function and can lead to severe knee deformity.
Yunfei Liu, Ruiyang Li, Yu Zhan, Xuetao Xie, Congfeng Luo   +4 more
doaj   +2 more sources

ATAC-seq reveals the roles of chromatin accessibility in the chondrocytes of Kashin–Beck disease compared with primary osteoarthritis [PDF]

Frontiers in Genetics, 2023
Objective: This study aimed to investigate the roles of accessible chromatin in understanding the different pathogeneses between Kashin–Beck disease (KBD) and primary osteoarthritis (OA).Methods: Articular cartilages of KBD and OA patients were collected,
Sen Wang, Yuanji Wang, Xingyu Li, Linlin Yuan, Xiong Guo, Mikko J. Lammi   +5 more
doaj   +2 more sources

Identifying discriminative features for diagnosis of Kashin-Beck disease among adolescents [PDF]

BMC Musculoskeletal Disorders, 2021
Introduction Diagnosing Kashin-Beck disease (KBD) involves damages to multiple joints and carries variable clinical symptoms, posing great challenge to the diagnosis of KBD for clinical practitioners.
Yanan Zhang, Xiaoli Wei, Chunxia Cao, Fangfang Yu, Wenrong Li, Guanghui Zhao, Haiyan Wei, Feng’e Zhang, Peilin Meng, Shiquan Sun, Mikko Juhani Lammi, Xiong Guo   +11 more
doaj   +2 more sources